[HTML][HTML] Regulation of glycogen synthase in rat hepatocytes: Evidence for multiple signaling pathways

L Lavoie, CJ Band, M Kong, JJM Bergeron… - Journal of Biological …, 1999 - ASBMB
… We examined the signaling pathways regulating glycogen synthase (… Taken together,
our results indicate that the signaling components … The regulation of glycogen synthase (GS), …

Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways

AS Manoukian, JR Woodgett - 2002 - Elsevier
… The name derives from studies by the Cohen group that classified various entities capable
of phosphorylating glycogen synthase (GS), the rate-limiting enzyme of glycogen synthesis. At …

Glycogen synthase kinase 3 in Wnt signaling pathway and cancer

N Tejeda‐Muñoz, M Robles‐Flores - IUBMB life, 2015 - Wiley Online Library
glycogen metabolism. Since then, GSK‐3 has been revealed as one of the master regulators
of a diverse range of signaling pathways, … ‐3 in Wnt signaling pathway and cancer using as …

The multifaceted roles of glycogen synthase kinase 3β in cellular signaling

CA Grimes, RS Jope - Progress in neurobiology, 2001 - Elsevier
… , a key regulatory process in the synthesis of glycogen. With such an inauspicious … many
cellular signaling pathways. Now it is known that GSK3β is an important component of signaling

[HTML][HTML] Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome

PK Dash, D Johnson, J Clark, SA Orsi, M Zhang… - PloS one, 2011 - journals.plos.org
… Studies have demonstrated that inhibition of glycogen synthase kinase-3 (GSK-3) effectively
reduces apoptosis following a number of stimuli. The Wnt family of proteins, and growth …

[HTML][HTML] Glycogen synthase kinase-3 signaling in Alzheimer's disease

E Lauretti, O Dincer, D Praticò - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
… In recent years, many signaling pathways associated with … of this condition including glycogen
synthase kinase-3β (GSK3… on its effects on specific signaling pathways associated with AD …

New insights into the role and mechanism of glycogen synthase activation by insulin

JC Lawrence Jr, PJ Roach - Diabetes, 1997 - Am Diabetes Assoc
signaling pathway via the phosphorylation of the regulatory subunit of glycogen synthase
phos… inactivates the enzyme glycogen synthase kinase-3 via the protein kinase B pathway, has …

Glycogen synthase kinase 3: a kinase for all pathways?

P Patel, JR Woodgett - Current topics in developmental biology, 2017 - Elsevier
… , its intercalation into a myriad of signaling pathways and the many proteins it regulates (we …
after all, there are only 15 or so distinct signaling pathways, and GSK-3 either plays a direct …

The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase

MR Gold, MP Scheid, L Santos… - The Journal of …, 1999 - journals.aai.org
We have previously shown that the B cell Ag receptor (BCR) activates phosphatidylinositol (PI)
3-kinase. We now show that a serine/threonine kinase called Akt or protein kinase B is a …

Defective insulin signaling pathway and increased glycogen synthase kinase‐3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction …

CG Jolivalt, CA Lee, KK Beiswenger… - Journal of …, 2008 - Wiley Online Library
… Our findings of impaired insulin signaling pathway activity and tau hyperphosphorylation
after 9 weeks of STZ-induced diabetes in mouse brain suggest that systemic insulin deficiency …