Glypican-3 and alphafetoprotein as diagnostic tests for hepatocellular carcinoma

J Filmus, M Capurro - Molecular Diagnosis, 2004 - Springer
… Immunohistochemical staining of hepatocellular carcinoma sections with the anti-glypican-3
(GPC3) 1G12 monoclonal antibody. (a) Low power picture of a GPC3-positive multinodular …

Diagnostic value of glypican-3 in alpha fetoprotein negative hepatocellular carcinoma patients

B Li, H Liu, HW Shang, P Li, N Li, HG Ding - African health sciences, 2013 - ajol.info
… However,the differential diagnosis between alpha fetoprotein(AFP) negative HCC and
cirrhotic nodules is still difficult. Objectives: To evaluate the diagnostic value of glypican-3(GPC3) …

A comparison of glypican-3 with alpha-fetoprotein as a serum marker for hepatocellular carcinoma: a meta-analysis

C Xu, Z Yan, L Zhou, Y Wang - Journal of cancer research and clinical …, 2013 - Springer
Backgrounds Glypican-3(GPC3) has been reported as one of the most promising serum
markers for hepatocellular carcinoma (HCC), while several studies have conflicting results for …

Glypican 3 has a higher sensitivity than alphafetoprotein for testicular and ovarian yolk sac tumour: immunohistochemical investigation with analysis of histological …

DL Zynger, JC McCallum, C Luan, PM Chou… - …, 2010 - Wiley Online Library
… Aims: Glypican 3 (GPC3) has been reported to be overexpressed in yolk sac tumour (YST),
but the sensitivity has not been compared with α-fetoprotein (AFP). YST can form numerous …

Hepatocellular oncofetal protein, glypican 3 is a sensitive marker for αfetoprotein‐producing gastric carcinoma

M Hishinuma, KI Ohashi, N Yamauchi… - …, 2006 - Wiley Online Library
… Aims Glypican 3 (GPC3) is a cell surface heparan sulphate proteoglycan expressed
specifically in the fetal liver and malignant neoplasms of hepatocyte lineage. The aim was to …

[HTML][HTML] Glypican-3 level assessed by the enzyme-linked immunosorbent assay is inferior to alpha-fetoprotein level for hepatocellular carcinoma diagnosis

Y Jeon, ES Jang, YS Choi, JW Kim… - Clinical and molecular …, 2016 - ncbi.nlm.nih.gov
Methods We enrolled 157 consecutive patients with newly diagnosed HCC and 156 patients
with liver cirrhosis (LC) as the control group. GPC3 plasma levels were measured using two …

[PDF][PDF] Glypican-3 versus alpha-fetoprotein as a biomarker for hepatocellular carcinoma: a diagnostic meta-analysis

W Fu, H Lu, L Li, K Wu, Y Li, Y Liu, J Hu - Biocell, 2015 - cdn.techscience.cn
Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a …
Diagnostic role of serum glypican-3 in differentiating hepatocellular carcinoma from non…

Expression of the glypican-3 gene in α-fetoprotein-negative human hepatocellular carcinoma

G Ding, H Wang, H Chen, M Wu, X Man… - The Chinese-German …, 2005 - Springer
Glypican-3 mRNA was intensively detected in 30 of 41 AFP-negative HCC (73.17%). In contrast,
Glypican3 … Serum alphafetoprotein in the early stage of human hepatocellular carcinoma…

Glypican 3‐expressing gastric carcinoma: Distinct subgroup unifying hepatoid, clear‐cell, and αfetoprotein‐producing gastric carcinomas

T Ushiku, H Uozaki, A Shinozaki, S Ota… - Cancer …, 2009 - Wiley Online Library
Glypican 3 was expressed in 11% of GC in the present study, of which 5% were diffuse-type
GPC3-GC and 6% were focal-type GPC3-GC. Diffuse-type GPC3-GC showed significantly …

Discovery and diagnostic value of a novel oncofetal protein: glypican 3

SK Wang, DL Zynger, O Hes… - Advances in anatomic …, 2014 - journals.lww.com
glypican 3 in germ cell tumors and other neoplasms in addition to hepatocellular carcinoma.
In conclusion, glypican 3 … -characterized α-fetoprotein (AFP). In this article, the expression of …