… The results illustrated that tadalafil had a significant antinociceptive effect in the tail flick, hot
plate, acetic acid-induced writhing and formalin tests indicating the involvement of peripheral …

… Therefore, the purpose of the present work was to examine whether a local activation of the
NO–cyclic GMP pathway has a role in the peripheral antinociceptive effect of nimesulide, a …

… the analgesic effect of dibutyryl cyclic GMP or acetylcholine (ACh… of the NO-cyclic GMP
pathway in ACh-induced analgesia, using … Dirksen and GJ Harty, 1985, Antinociceptive effects of …

… also indicated that the antinociceptive effect of crotalphine is … opioid receptors in the
antinociceptive effect of crotalphine in the … mechanisms responsible for this effect have not yet …

… of tolerance to morphine antinociceptive effect, as indicated … of tolerance to morphine
antinociceptive effect in both the tail-… In conclusion, we found that activation of the NO–cyclic GMP …

… In contrast, we have evidence that not all NSAIDs act through this pathway (López-Muñoz
et … NO–cyclic GMP pathway is involved in the peripheral antinociceptive effect of meloxicam, …

… by itself, but increased the effect of ketorolac. The present results suggest that the antinociceptive
effect of ketorolac involves activation of the NO–cyclic GMP pathway, followed by an …

… -gated cation channels (Barnstable et al., 2004) and cyclic GMP-regulated … the antinociceptive
effect of N 2 O is mediated by a signaling pathway, which involves NO, cyclic GMP and …

… This study tested the hypothesis that the acute antinociceptive effect of HBO 2 is mediated
by a signaling pathway in which there is sequential activation of NOS, sGC, protein kinase G …

… antinociceptive effects … antinociception against the first and second phases of the formalin
test, with mean ID 50 values of 28.17 and 39.68 mg/kg, respectively. The antinociceptive effect …