Nitric oxide–cyclic GMP pathway with some emphasis on cavernosal contractility

IF Ghalayini - International journal of impotence research, 2004 - nature.com
Nitric oxide (NO) is formed from the conversion of L-arginine by nitric oxide synthase (NOS),
which exists in three isoforms: neuronal (nNOS), endothelial (eNOS), and inducible (iNOS). …

Nitric oxide and cyclic GMP signaling

LJ McDonald, F Murad - Proceedings of the Society for …, 1996 - journals.sagepub.com
Conclusions NO and cGMP constitute an autocrine, paracrine, and possible endocrine signal
transduction system. Cytosolic NO-responsive guanylyl cyclase can be stimulated by NO …

The nitric oxide-cyclic GMP signalling pathway in rat brain

E Southam, J Garthwaite - Neuropharmacology, 1993 - Elsevier
… region did we observe cyclic GMP accumulation in the absence of nitric oxide synthase
staining. In … In some areas, nitric oxide synthase was found in postsynaptic structures and cyclic …

Peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway

IDG Duarte, BB Lorenzetti, SH Ferreira - European Journal of …, 1990 - Elsevier
… cyclic GMP or acetylcholine (ACh) injected into rat paws. Since ACh induces nitric oxide (NO…
the possible involvement of the NO-cyclic GMP pathway in ACh-induced analgesia, using a …

[HTML][HTML] A New Pathway of Nitric Oxide/Cyclic GMP Signaling InvolvingS-Nitrosoglutathione

B Mayer, S Pfeiffer, A Schrammel, D Koesling… - Journal of Biological …, 1998 - ASBMB
Nitric oxide (NO), a physiologically important activator of soluble guanylyl cyclase (sGC), is
synthesized from l-arginine and O 2 in a reaction catalyzed by NO synthases (NOS). Previous …

[13] Nitric oxide-cyclic GMP signal transduction system

AJ Hobbs, LJ Ignarro - Methods in enzymology, 1996 - Elsevier
Nitric Oxide Synthesis Nitric oxide is generated via a five-electron oxidation of a terminal …
-electron oxidation is facilitated by a single enzyme, nitric oxide synthase (NOS). On the basis of …

The nitric oxide/cyclic GMP pathway: a potential major regulator of cochlear physiology

JD Fessenden, J Schacht - Hearing research, 1998 - Elsevier
… In brief, nitric oxide (NO) is formed by the enzyme nitric oxide … The product of the reaction
catalyzed by sGC is cyclic GMP, a … Nitric oxide was originally characterized as an air pollutant in …

Two pathways of cyclic GMP production through glutamate receptor‐mediated nitric oxide synthesis

D Okada - Journal of neurochemistry, 1992 - Wiley Online Library
… (Garthwaite et al., 1989), increase the cyclic GMP (cGMP) content in the cerebellum through
activation of neural nitric oxide synthase (NOS), a calmodulindependent enzyme (Bredt and …

Possible role of nitric oxide-cyclic GMP pathway in object recognition memory: effects of 7-nitroindazole and zaprinast

J Prickaerts, HWM Steinbusch, JFM Smits… - European journal of …, 1997 - Elsevier
The effects of 7-nitroindazole, a putative selective inhibitor of neuronal nitric oxide (NO)
synthase and zaprinast, a cGMP-selective phosphodiesterase inhibitor, were evaluated on …

The nitric oxide/cyclic GMP pathway in organ transplantation: critical role in successful lung preservation.

DJ Pinsky, Y Naka, NC Chowdhury… - Proceedings of the …, 1994 - National Acad Sciences
Reestablishment of vascular homeostasis following ex vivo preservation is a critical determinant
of successful organ transplantation. Because the nitric oxide (NO) pathway modulates …