Localized nature of the transition-state structure in goat α-lactalbumin folding

K Saeki, M Arai, T Yoda, M Nakao… - Journal of molecular …, 2004 - Elsevier
… folding intermediate of goat α-lactalbumin is further organized in … state of goat α-LA is not
extensively distributed over the α-… of α-lactalbumin has a partially formed structure inside the α-…

Kinetics of folding and unfolding of goat αlactalbumin

A Chedad, H Van Dael - Proteins: Structure, Function, and …, 2004 - Wiley Online Library
… The folding rate of bovine α-lactalbumin (… of goat α-lactalbumin (GLA) in the absence
and in the presence of Ca 2+ ions and at different pH values. It is well-known that in α-lactalbumins

Protein profile and alpha-lactalbumin concentration in the milk of standard and transgenic goats expressing recombinant human butyrylcholinesterase

H Baldassarre, M Schirm, J Deslauriers, C Turcotte… - Transgenic …, 2009 - Springer
… on day 1 of lactation in transgenic goats (4.33 ± 0.97 vs. 2.24 ± … α-lactalbumin gene may
be the cause for the delayed start of milk production observed in this herd of transgenic goats

The amino acid sequence of goat α-lactalbumin

RTA Macgillivray, K Brew, K Barnes - Archives of Biochemistry and …, 1979 - Elsevier
… analysis of human and guinea pig a-lactalbumins (5, 6) and by … sequence of a-la&albumin
from goat milk, to provide additional … Goat a-lactalbumin, which has been the subject of some …

Expression of goat α-lactalbumin in Escherichia coli and its refolding to biologically active protein

I Kumagai, S Takeda, T Hibino… - … Engineering, Design and …, 1990 - academic.oup.com
… -length cDNA encoding goat pre a-lactalbumin (Kumagai et al.… expression system for goat
a-lactalbumin in Escherichia colias … of a-lactalbumin, the active a-lactalbumin was refolded and …

Photoexcitation of tryptophan groups induces reduction of two disulfide bonds in goat α-lactalbumin

A Vanhooren, B Devreese, K Vanhee… - Biochemistry, 2002 - ACS Publications
Illumination of goat α-lactalbumin (GLA) with 280 or 295 nm light results in tryptophan-mediated
photolysis of disulfide bonds within the protein. The photolysis is not dependent on the …

Production of transgenic dairy goat expressing human α-lactalbumin by somatic cell nuclear transfer

X Feng, S Cao, H Wang, C Meng, J Li, J Jiang… - Transgenic …, 2015 - Springer
… Production of human α-lactalbumin (hα-LA) transgenic cloned dairy goats has great … the
yield of dairy goat milk. Here, a mammary-specific expression vector 5A, harboring goat β-…

Expression of Recombinant Human AlphaLactalbumin in the Milk of Transgenic Goats Using a Hybrid Pomoter/Enhancer

YG Yuan, L An, B Yu, S Song, F Zhou… - Journal of Analytical …, 2014 - Wiley Online Library
… of goat milk, we describe the construction of a vector (pBLAC) containing a hybrid goat β-…
We also describe the generation of transgenic goats expressing rhLA by somatic cell nuclear …

Crystal structures of guinea-pig, goat and bovine α-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose …

ACW Pike, K Brew, KR Acharya - Structure, 1996 - cell.com
Background: The regulation of milk lactose biosynthesis is highly dependent on the action
of a specifier protein, α-lactalbumin (LA). Together with a glycosyltransferase, LA forms the …

Sequence of the goat α-lactalbumin-encoding gene: comparison with the bovine gene and evidence of related sequences in the goat genome

JL Vilotte, S Soulier, C Printz, JC Mercier - Gene, 1991 - Elsevier
… of a genomic clone encoding goat a-lactalbumin (rLA) are … two small insertions were found
in the goat sequence. One of these … sequences in the goat genome, as previously observed in …