… with good performance status, some patients present with poor clinical conditions. The
best … of patients with metastatic colorectal cancer and poor performance status, defined as …

… with histologically proven metastatic colorectal cancer, referred for chronomodulated
chemotherapy, were registered in the study; 52% of the patients had two or more metastatic sites, …

Background The management of metastatic colorectal cancer patients with a poor performance
status (PS) continues to be a clinical dilemma, with the potential activity and safety of …

… /MSI-H) metastatic colorectal cancer (mCRC), but clinical decision-making in this rapidly
evolving treatment landscape is challenging. Since performance status (PS) represents a well-…

… Four rhythms known to reflect circadian clock function were studied in 18 patients with
metastatic colorectal cancer and good performance status. Rest–activity was monitored by wrist …

… In this subgroup of patients, multidrug therapy offered better … or 4 with a tendency to have
better OS than those treated with … to patients with poor performance status. We conducted a …

… with metastatic colorectal cancer (… with good performance.2, 3, 4 Currently we have scarce
data to evaluate whether such benefits apply equally to patients with poor performance status (…

… [11], [12], [13] These studies, however, excluded patients with poor performance status so …
well-tolerated agent against metastatic colorectal cancer with efficacy similar to or even better …

… Performance status (PS) is known as one of the strongest prognostic factors for survival in
metastatic colorectal cancer … It is well known that PS is a strong prognostic factor for survival in …

… In the multivariate analysis (Table 2), the variables associated with a better outcome were
good performance status (ECOG 0), reduced dose associated with a greater number of cycles, …