Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis

J Padmanabhan, DS Park, LA Greene… - Journal of …, 1999 - Soc Neuroscience
… in KCl withdrawal-induced apoptosis of cerebellar granule neurons, we initially assessed
whether … Because caspases have been implicated in many models of neuronal apoptosis, we …

Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons

A Valencia, J Morán - Journal of neuroscience research, 2001 - Wiley Online Library
… In this study we analyzed the role of oxidative stress and its relationship to [Ca 2+ ] i and
caspase activation in neuronal apoptotic cell death using CGN apoptotic death as a model of …

PACAP protects cerebellar granule neurons against oxidative stress‐induced apoptosis

D Vaudry, TF Pamantung, M Basille… - European Journal of …, 2002 - Wiley Online Library
… Oxidative stress, resulting from accumulation of reactive oxygen species, plays a critical
role in neuronal cell death associated with neurodegenerative diseases and stroke. In the …

Apoptosis and autophagy in rat cerebellar granule neuron death: Role of reactive oxygen species

P Maycotte, A Guemez‐Gamboa… - Journal of neuroscience …, 2010 - Wiley Online Library
… In this work, we characterize apoptotic and autophagic cell death in rat cerebellar granule
neuron (CGN) culture, a widespread model for the study of neuronal death. Potassium …

Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

C Galli, A Piccini, MT Ciotti… - Proceedings of the …, 1998 - National Acad Sciences
… Herein we show that neuronal apoptosis is associated with an increase of amyloidogenic
metabolism, indicating that different causes may, therefore, lead to a common …

Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons

GM Yan, B Ni, M Weller, KA Wood, SM Paul - Brain research, 1994 - Elsevier
… of neurotoxicity which is non-apoptotic in nature. Given the … in preventing apoptosis of
cultured cerebellar granule neurons, … granule neurons are among the most abundant neuronal

Cultured cerebellar granule neurons as a model of neuronal apoptosis

GM Yan, SM Paul - Apoptosis Techniques and Protocols, 1997 - Springer
apoptosis of cultured cerebellar granule neurons. Activation of specific G proteins robustly
and bidirectionally affects apoptosis of cultured cerebellar granule neurons (… blocks apoptosis

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease: evidence for apoptotic cell death

C Stadelmann, TL Deckwerth, A Srinivasan… - The American journal of …, 1999 - Elsevier
… , induces apoptosis.5, 6 Apoptotic neuronal cell death has been observed in primary cultures
of Down's syndrome (DS. neurons, 7 and altered expression of apoptosis related proteins, …

Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure

A Fiedorowicz, I Figiel, B Kamińska, M Zaremba, S Wilk… - Brain research, 2001 - Elsevier
… To study, if prolyl oligopeptidase is engaged in neuronal apoptosis following TMT … dose,
indicating the lack of prolyl oligopeptidase contribution to neuronal injury caused by TMT. The …

K+-dependent cerebellar granule neuron apoptosis: role of TASK leak K+ channels

I Lauritzen, M Zanzouri, E Honoré, F Duprat… - Journal of Biological …, 2003 - ASBMB
… protects cerebellar granule neurons. Neuronal death of cultured rat granule neurons is
also … K + channels might be involved in in vitro K + -dependent granule neuronal apoptosis. …