过去一年中添加的文章,按日期排序

CDK4/6 inhibitors potently inhibit cell viability in pre-clinical models of adult-type ovarian granulosa cell tumors

A Brodsky, T Welte, AF Legarreta… - Gynecologic …, 2024 - gynecologiconcology-online.net
6 天前 - … metastatic, hormone receptor-positive breast cancer compared to hormone therapy
alone. … Since antiestrogen therapy is a mainstay of treatment for adult granulosa cell tumors (…

[HTML][HTML] Pathohistological Findings after Bilateral Ovariectomy in Mares with Behavioral Problems

N Wolf, JA Hahn, I Walter, Y Zablotski, H Zerbe… - Animals, 2024 - mdpi.com
6 天前 - … for behavioral problems is the commonly occurring granulosa cell or granulosa-theca
cell tumor, abbreviated as GCT in this study, due to excessive hormonal activity [7,8]. …

[PDF][PDF] 8060 SIRT4 Plays a Role in Mammary Gland Development

B deSouza, F Huynh, K Anderson… - Journal of the …, 2024 - academic.oup.com
10 天前 - … In ovaries of adult mice, SIRT4 is most highly expressed in differentiated
granulosa cells of the corpus luteum, a temporary endocrine structure responsible for synthesizing …

Anti-Müllerian hormone signaling in the ovary involves stromal fibroblasts: a study in humans and mice provides novel insights into the role of ovarian stroma

I Spector, S Derech-Haim, I Boustanai… - Human …, 2024 - academic.oup.com
11 天前 - … around follicles at all developmental stages exhibit high AMHR2 expression, while
granulosa cells of growing follicles show considerably lower levels. The majority of these …

[HTML][HTML] An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis

JD Lehle, YH Lin, A Gomez, L Chavez, JR McCarrey - eLife, 2024 - elifesciences.org
11 天前 - hormone receptors. We exposed cultured pluripotent (iPS), somatic (Sertoli and
granulosa), and primordial germ cell-like (PGCLC) cells … of relevant hormone receptors inducing …

[HTML][HTML] Androgen receptor expression in recurrent granulosa cell tumor of the ovary: Clinical considerations of treatment and surveillance in a transgender male

J Tumas, RDA Hiraldo, T Berman - Gynecologic Oncology Reports, 2024 - Elsevier
26 天前 - … is no standardized dosing schedule, and hormone receptor expression of the tumors
was not … Novel triple hormonal therapy using an androgen receptor antagonist, aromatase …

Mechanisms and effects of AdipoRon, an adiponectin receptor agonist, on ovarian granulosa cells—a systematic review

LF Laurindo, LF Laurindo, VD Rodrigues… - Naunyn-Schmiedeberg's …, 2024 - Springer
26 天前 - … By examining studies involving various models—ranging from in vitro granulosa
cells of rats and laying hens to human luteinized granulosa cells and chicken ovary follicles—…

[HTML][HTML] Impact of Amphiregulin on Oocyte Maturation and Embryo Quality: Insights from Clinical and Molecular Perspectives

M Kljajic, JT Ney, G Wagenpfeil, S Baus… - Geburtshilfe und …, 2024 - thieme-connect.com
28 天前 - … Altered amphiregulin expression induced by diverse luteinizing hormone receptor
reactivity in granulosa cells affects IVF outcomes. Reprod Biomed Online 2015; 30: 593-601 …

FecBB mutation enhances follicle stimulating hormone sensitivity of granulosa cells by up-regulating the SMAD1/5–USF1–FSHR signaling pathway

Y Jiao, Y Zhu, J Guo, X Jiang, X Liu, Y Chen… - International Journal of …, 2024 - Elsevier
28 天前 - … Here, we report the creation of a human granulosa cell, COV434, model containing
a homozygous FecB B mutation through homology-directed repair (HDR) induced by …

[PDF][PDF] Which is the current knowledge on man-made endocrine-disrupting chemicals in follicular fluid? An overview of effects on ovarian function and reproductive …

AM Shulhai, V Bianco, V Donini, SM Esposito… - Frontiers in …, 2024 - frontiersin.org
34 天前 - … , impacting not only granulosa cell function but also other surrounding ovarian …
-cultured human granulosa cells and a steroidogenic human granulosa-like tumor cell line …