The process of ovarian aging: it is not just about oocytes and granulosa cells

A Camaioni, MA Ucci, L Campagnolo… - Journal of assisted …, 2022 - Springer
women revealed a greater degree of vacuolization and crista malformation in the older
granulosa cells, … have also been documented in GCs of women older than 38 years of age [61], …

A distinctive epigenetic ageing profile in human granulosa cells

KW Olsen, J Castillo-Fernandez, A Zedeler… - Human …, 2020 - academic.oup.com
… mural granulosa cells (MGC) calculated with the Granulosa Cell clock. (B) Scatter plot showing
the Granulosa Cellscells at the time of follicular recruitment in older women is impaired. …

Role of granulosa cells in the aging ovarian landscape: a focus on mitochondrial and metabolic function

HC Alberico, DC Woods - Frontiers in Physiology, 2022 - frontiersin.org
… to granulosa cell function. Herein, we provide a review of the literature pertaining to the role
of … in granulosa cell function, with emphasis on how mitochondrial aging in granulosa cells

[HTML][HTML] Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes

SLP Regan, PG Knight, JL Yovich, F Arfuso… - Fertility and sterility, 2018 - Elsevier
granulosa cell GHR density in different sized follicles from IVF patients undergoing conventional
ovarian stimulation in young compared with older women … receptor density in older, poor …

Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women

A Brzezinski, A Saada, H Miller… - Journal of ovarian …, 2018 - Springer
… Five young women and five older women were enrolled in this study. Indication for in-vitro
fertilization treatment included unexplained, mechanical or male infertility. As expected, young …

[HTML][HTML] The aging ovary—the poor granulosa cells

C Tatone, F Amicarelli - Fertility and sterility, 2013 - Elsevier
… of oxidative stress in aged granulosa cells. The second part … compartments, including granulosa
cells and ovarian interstitial … on stress signaling pathways in older granulosa cells 26, 27. …

Effects of aging on ovarian fecundity in terms of the incidence of apoptotic granulosa cells

SH Sadraie, H Saito, T Kaneko, T Saito… - Journal of assisted …, 2000 - Springer
… Results: Granulosa cells in the older women revealed a … The mural granulosa cells were
then hormone (LH) of the women in the present study were in normal range. The women were …

Anti-Müllerian hormone level in older women: detection of granulosa cell tumor recurrence

YH Chong, AJ Campbell, S Farrand… - International Journal of …, 2012 - ijgc.bmj.com
women older than 65 years. This extends the normative data for AMH to 108 years old,
providing a reference range for the detection of granulosa cell tumors in postmenopausal women. …

Granulosa cell tumor of the ovary

ST Schumer, SA Cannistra - Journal of clinical oncology, 2003 - ascopubs.org
… In older women, a total abdominal hysterectomy and bilateral salpingooophorectomy are
typically performed. In womenGRANULOSA CELL tumor (GCT) of the ovary is an uncommon …

Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells

C Tatone, MC Carbone, S Falone… - Molecular human …, 2006 - academic.oup.com
granulosa cells (GCs) from periovulatory follicles. GCs employed in this study were obtained
from follicular aspirates of 20 younger women (range 27–32 years) and 20 older women (…