Granulosa cells as hormone targets: the role of biologically active follicle-stimulating hormone in reproduction
AJW Hsueh, TA Bicsak, XC Jia, KD Dahl… - Proceedings of the 1988 …, 1989 - Elsevier
… shown that granulosa cells contain the type II regulatory subunit (R-… R-II identified, with
apparent M r of 54,000, 52,000, and 51,000. FSH treatment increased the amount of R-II 51 and R…
apparent M r of 54,000, 52,000, and 51,000. FSH treatment increased the amount of R-II 51 and R…
A Specific FSH Receptor in Rat Granulosa Cells: Properties of Binding in Vitro
A NIMROD, GF ERICKSON, KJ Ryan - Endocrinology, 1976 - academic.oup.com
… hypothesized that these rat granulosa cells contain specific FSH receptors. Since this was …
FSH receptor in granulosa cells isolated from these animals. Incubating these granulosa cells …
FSH receptor in granulosa cells isolated from these animals. Incubating these granulosa cells …
FSH induction of functional LH receptors in granulosa cells cultured in a chemically defined medium
GF Erickson, C Wang, AJW Hsueh - Nature, 1979 - nature.com
… LH/hCG receptors can be induced by FSH in isolated granulosa cells cultured in a chemically
defined medium, but not in isolated granulosa cells cultured with serum. In addition, we …
defined medium, but not in isolated granulosa cells cultured with serum. In addition, we …
[HTML][HTML] … in gene expression of granulosa cells from women undergoing controlled ovarian hyperstimulation with either recombinant follicle-stimulating hormone or …
ML Grøndahl, R Borup, YB Lee, V Myrhøj, H Meinertz… - Fertility and sterility, 2009 - Elsevier
… expression in the mural granulosa cells after COH using either recombinant FSH or hMG. …
the hMG-treated mural granulosa cells as compared with recombinant FSH–treated cells (Fig. 2…
the hMG-treated mural granulosa cells as compared with recombinant FSH–treated cells (Fig. 2…
[HTML][HTML] Differential gene expression in human granulosa cells from recombinant FSH versus human menopausal gonadotropin ovarian stimulation protocols
J Brannian, K Eyster, BA Mueller, MG Bietz… - Reproductive Biology …, 2010 - Springer
… of tissue or isolated cells. The purpose of this study was to test the hypothesis that granulosa
cell (GC) gene expression response differs between pure recombinant FSH and human …
cell (GC) gene expression response differs between pure recombinant FSH and human …
Recombinant human gonadotropins stimulate steroid and inhibin production in human granulosa cells
C Bergh, U Selleskog, T Hillensjö - European journal of …, 1997 - academic.oup.com
… in human granulosa cells. In the present study the effects of recombinant FSH (rFSH) and
LH (rLH) on steroid and inhibin production were examined in human granulosa cells in culture. …
LH (rLH) on steroid and inhibin production were examined in human granulosa cells in culture. …
FSH Stimulation promotes progesterone synthesis and output from human granulosa cells without luteinization
… The samples were treated with recombinant FSH at 12.5, 25 and 50 mIU/ml concentrations
for 24 and 48 h (Gonal-F © ; follitropin alpha, Merck Serono, Turkey). DMEM-F12 culture …
for 24 and 48 h (Gonal-F © ; follitropin alpha, Merck Serono, Turkey). DMEM-F12 culture …
The glycan structure in recombinant human FSH affects endocrine activity and global gene expression in human granulosa cells
N Loreti, C Fresno, D Barrera, L Andreone… - Molecular and cellular …, 2013 - Elsevier
… to different recombinant human FSH (rhFSH) glycosylation variants on the endocrine activity
and gene expression at whole-genome scale in human granulosa-like tumor cell line, KGN. …
and gene expression at whole-genome scale in human granulosa-like tumor cell line, KGN. …
Hypoglycosylated hFSH has greater bioactivity than fully glycosylated recombinant hFSH in human granulosa cells
C Jiang, X Hou, C Wang, JV May… - The Journal of …, 2015 - academic.oup.com
… acting directly on FSH receptors (FSHR) located on granulosa cells (1–3). Glycosylation of …
recombinant hFSH glycoforms, FSH 21/18 , and FSH 24 , and the KGN human granulosa cell …
recombinant hFSH glycoforms, FSH 21/18 , and FSH 24 , and the KGN human granulosa cell …
Establishment of steroidogenic granulosa cell lines expressing follicle stimulating hormone receptors
I Keren-Tal, A Dantes, R Sprengel… - Molecular and cellular …, 1993 - Elsevier
… In this work, we succeeded in establishing oncogene-transformed granulosa cell lines that
express constitutively FSH receptors. This could be achieved only if the cells, which had lost …
express constitutively FSH receptors. This could be achieved only if the cells, which had lost …
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