… Drugs interacting with grapefruit juice Summary of studied drugs Most medications
investigated for an interaction with grapefruit juice are substrates for CYP3A4 (Table 1). The most …

… of grapefruit products with drugs is best done on an individual drug basis rather than collectively
by drug … recipients, its interaction with grapefruit juice is likely to be clinically significant. …

… interaction between grapefruit juice and various drugs, focusing on different aspects: interaction
mechanisms, grapefruit juice … for the interaction, drugs exhibiting the interaction and the …

… from previous drug interaction studies, where high doses of grapefruit juice had been …
between grapefruit juice and caffeine.5 In this study of 12 healthy adults, 300 ml grapefruit juice (1 …

… with a potential for drug interactions in GFJ−drug interaction studies. The concentration of …
interaction and impair direct comparison of studies in which different juices have been used. …

… This review addressed drug interactions precipitated by fruit juices other than grapefruit juice
… simply addressed pharmacodynamic interactions and 33 RCTs studied pharmacokinetic …

… are daily consumed and often taken together with drugs. Therefore, … grapefruit juice and
grapefruit itself have been investigated as a basis of prediction for grapefruit–drug interaction in …

… Abstract: This study aims to assess utility and limitations of grapefruit juice (GFJ) interaction
… of GFJ with or up to 4 h before drug intake, and a reported significant increase in AUC in the …

… In the present study we systematically investigated in vitro the potential drug interaction
between selected ingredients of GFJ and the P‐gp transporter system, using talinolol (100 µM) …

… As a result, felodipine is the most studied probe for grapefruit juice-drug interactions. …
confirmed that naringin was not the causative constituent of grapefruit juice-drug interactions. …