The greater impact of PNPLA3 polymorphism on liver‐related events in Japanese non‐alcoholic fatty liver disease patients: A multicentre cohort study

Y Seko, K Yamaguchi, T Shima, M Iwaki… - Liver …, 2023 - Wiley Online Library
… In this study, we investigated the epidemiology of NAFLD and the impact of PNPLA3 on …
of PNPLA3 variants differs among races, studies on the effects of PNPLA3 polymorphisms on …

PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease

J Shen, GLH Wong, HLY Chan… - Journal of …, 2015 - Wiley Online Library
PNPLA3 polymorphism had no impact on IHTG changes in the control group. By multivariable
analysis, PNPLA3 … In this study, PNPLA3 rs738409 gene polymorphism was determined in …

Association between PNPLA3 rs738409 polymorphism and nonalcoholic fatty liver disease: a systematic review and meta-analysis

N Salari, N Darvishi, K Mansouri, H Ghasemi… - BMC endocrine …, 2021 - Springer
… Another meta-analysis conducted in 2019 stated that this polymorphism had a major impact
on the development of tissue damage in liver and that the G allele was considered as a risk …

PNPLA3 gene polymorphism is associated with predisposition to and severity of alcoholic liver disease

H Salameh, E Raff, A Erwin, D Seth… - Official journal of the …, 2015 - journals.lww.com
… evidence of AFL, ALI, AC, or HCC irrespective of their drinking status as our primary aim
was to examine the association of PNPLA3 polymorphisms with the predisposition to ALD. …

PNPLA3 gene polymorphism accounts for fatty liver in community subjects without metabolic syndrome

J Shen, GLH Wong, HLY Chan… - Alimentary …, 2014 - Wiley Online Library
… We were thus unable to evaluate the impact of PNPLA3 polymorphism on liver injury at the
… the impact of PNPLA3 on long-term clinical outcomes. To this end, PNPLA3 polymorphism

Carriage of the PNPLA3 rs738409 C> G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma

YL Liu, GL Patman, JBS Leathart, AC Piguet… - Journal of …, 2014 - Elsevier
… Consistent with a recent report that PNPLA3 genotype may have a greater impact on … exerts
a greater effect. Stratification by median age showed the greatest effect of PNPLA3 in those …

Impact of the association between PNPLA3 genetic variation and dietary intake on the risk of significant fibrosis in patients with NAFLD

E Vilar-Gomez, CJ Pirola, S Sookoian… - Official journal of the …, 2021 - journals.lww.com
… a relationship between PNPLA3 rs738409 and foods rich in … significant relationship between
PNPLA3 rs738409 and nutrient … fibrosis severity might be modulated by PNPLA3 rs738409. …

PNPLA3 gene in liver diseases

E Trépo, S Romeo, J Zucman-Rossi, P Nahon - Journal of hepatology, 2016 - Elsevier
… Liver diseases have a significant impact on worldwide … reported that single nucleotide
polymorphisms (SNPs) located in … (here HCV) downplayed the impact of PNPLA3 on steatosis and …

[HTML][HTML] PNPLA3 as a genetic determinant of risk for and severity of non-alcoholic fatty liver disease spectrum

H Salameh, M Al Hanayneh, M Masadeh… - Journal of clinical and …, 2016 - ncbi.nlm.nih.gov
PNPLA3 polymorphisms with the spectrum and severity of this disease. Methods: Studies
evaluating the association between the PNPLA3 polymorphism … ability to examine the impact of …

Impact of PNPLA3 and IFNL3 polymorphisms on hepatic steatosis in Asian patients with chronic hepatitis C

CM Huang, KC Chang, CH Hung, KW Chiu, SN Lu… - PloS one, 2017 - journals.plos.org
… A recent meta-analysis revealed that the genotype PNPLA3 … association of PNPLA3 and
IFNL3 polymorphisms with HS in … association of PNPLA3 and IFNL3 polymorphisms with HS in …