Vascular endothelial growth factor–targeted therapy in renal cell carcinoma: current status and future directions
BI Rini - Clinical Cancer Research, 2007 - AACR
… by angiogenic growth factors, such as vascular endothelial growth factor (VEGF), platelet-derived
growth factor (PDGF), and basic fibroblast growth factor (3). VEGF is the major factor …
growth factor (PDGF), and basic fibroblast growth factor (3). VEGF is the major factor …
Biology and clinical development of vascular endothelial growth factor–targeted therapy in renal cell carcinoma
BI Rini, EJ Small - Journal of Clinical Oncology, 2005 - ascopubs.org
… vascular endothelial growth factor (VEGF) -directed agents in renal cell carcinoma. Bevacizumab
… VEGFR-2, vascular endothelial growth factor receptor type 2; PI3K, phosphoinositide 3-…
… VEGFR-2, vascular endothelial growth factor receptor type 2; PI3K, phosphoinositide 3-…
Vascular endothelial growth factor as prognostic factor in renal cell carcinoma
JAN Jacobsen, T Rasmuson, K Grankvist… - The Journal of …, 2000 - auajournals.org
… growth factor (VEGF) has been recognized as an important constituent of vascularization
and growth of solid … findings and clinical outcome in patients with renal cell carcinoma (RCC). …
and growth of solid … findings and clinical outcome in patients with renal cell carcinoma (RCC). …
Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck
ME Sharafinski, RL Ferris, S Ferrone… - Head & neck, 2010 - Wiley Online Library
… Cumulative evidence implicates the epidermal growth factor receptor (EGFR) as an important
therapeutic target in head and neck squamous cell carcinoma (HNSCC). The basis for the …
therapeutic target in head and neck squamous cell carcinoma (HNSCC). The basis for the …
Quantitative immunohistochemical analysis of transforming growth factor‐α and epidermal growth factor receptor in patients with squamous cell carcinoma of the head …
JR Grandis, MF Melhem, EL Barnes… - … Journal of the …, 1996 - Wiley Online Library
… patients, and squamous cell carcinomas) we were able to localize growth factor production
to specific epithelial cells (eg, basal, suprabasal epithelial cells, and tumor cells). The change …
to specific epithelial cells (eg, basal, suprabasal epithelial cells, and tumor cells). The change …
Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma
M Maurizi, G Almadori, G Ferrandina… - British Journal of …, 1996 - nature.com
… Summary Epidermal growth factor receptor (EGFR) content was determined by a radioligand
receptor assay in 140 primary laryngeal squamous cell carcinomas (median value of 8.4 …
receptor assay in 140 primary laryngeal squamous cell carcinomas (median value of 8.4 …
… , a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
RJ Motzer, MD Michaelson, BG Redman… - Journal of Clinical …, 2006 - ascopubs.org
… Renal cell carcinoma (RCC) is characterized by loss of von Hippel Lindau tumor suppressor
… growth factors: vascular endothelial growth factor (VEGF) and platelet-derived growth factor (…
… growth factors: vascular endothelial growth factor (VEGF) and platelet-derived growth factor (…
Expression of vascular endothelial growth factor protein in human renal cell carcinoma
J Jacobsen, K Grankvist, T Rasmuson… - BJU …, 2004 - Wiley Online Library
… growth factor, platelet derived growth factor, epidermal growth factor and vascular endothelial
growth factor (VEGF), the most potent mitogenic factor [1] In RCC it has been shown that up…
growth factor (VEGF), the most potent mitogenic factor [1] In RCC it has been shown that up…
Clinical implications of the expression of epidermal growth factor receptors in human transitional cell carcinoma
EM Messing - Cancer research, 1990 - AACR
… Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of
epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine …
epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine …
Vascular endothelial growth factor expression is increased in renal cell carcinoma
… cells resulting in cellular proliferation. Elevated levels of epidermal growth factor (EGF) and
basic fibroblast growth factor (… .3, 4 Although these growth factors are known stimulators of …
basic fibroblast growth factor (… .3, 4 Although these growth factors are known stimulators of …
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