Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro.

Y Nakanishi, JL Mulshine, PG Kasprzyk… - The Journal of …, 1988 - Am Soc Clin Investig
… insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was
Growth factor effects on small cell lung cancer cells using a colorimetric assay: can a transfer…

Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells

RJ Pietras, DC Márquez, HW Chen, E Tsai… - Steroids, 2005 - Elsevier
… , and by disruption of associated membrane growth factor receptor signaling. The results …
leading to modulation of the growth and survival of breast and non-small cell lung cancers. …

Cell adhesion molecules, vascular endothelial growth factor, and basic fibroblast growth factor in patients with non–small cell lung cancer treated with chemotherapy …

A Dowlati, R Gray, AB Sandler, JH Schiller… - Clinical Cancer …, 2008 - AACR
factors for response to another class of targeted therapies in lung cancer, epidermal
growth factor receptor inhibitors, have been extensively reported (7), no predictive factors for …

Update on Epidermal Growth Factor Receptor Mutations in Non–Small Cell Lung Cancer

GJ Riely, KA Politi, VA Miller, W Pao - Clinical Cancer Research, 2006 - AACR
growth factor receptor gene were associated with clinical responses to erlotinib and gefitinib
in patients with non–small cell lung cancer. … with non–small cell lung cancer. Although a …

Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non–small-cell lung cancer

J Nemunaitis, RO Dillman… - Journal of Clinical …, 2006 - ascopubs.org
… II, IIIA, IIIB, and IV non–small-cell lung cancer patients. Each patient received one of three
doses (1.25, 2.5, or 5.0 × 10 7 cells/injection) of belagenpumatucel-L on a monthly or every …

Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers

S Savic, C Tapia, B Grilli, A Rufle, MP Bihl… - … journal of cancer, 2008 - nature.com
… Epidermal growth factor receptor (EGFR) gene mutations and increased copy numbers are
… ) in non-small-cell lung cancer (NSCLC). Lung cancer diagnosis is often based on cytology …

Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer …

G Fontanini, M De Laurentiis, S Vignati, S Chine… - … Association for Cancer …, 1998 - AACR
growth factor alpha (TGF alpha), amphiregulin (AR), CRIPTO, the epidermal growth factor
receptor (EGFR), erbB-2, erbB-3, and tumor … I-IIIA non-small cell lung cancer (NSCLC) treated …

Epidermal growth factor receptor inhibitors in development for the treatment of non–small cell lung cancer

JV Heymach, M Nilsson, G Blumenschein… - Clinical cancer …, 2006 - AACR
growth factor receptor (EGFR) pathway can prolong survival in patients with non–small cell
lung cancer … In the Iressa Survival Evaluation in Lung Cancer trial, no significant prolongation …

… transducer and activator of transcription 3 is required for the oncogenic effects of non–small-cell lung cancer–associated mutations of the epidermal growth factor …

JV Alvarez, H Greulich, WR Sellers, M Meyerson… - Cancer research, 2006 - AACR
… of lung cancer cells expressing mutant EGFRs. We next determined whether STAT3 plays
a role in the growth and survival of lung cancer cells with mutant EGFRs. HCC-827 cells were …

The role of the insulin-like growth factor signaling pathway in non-small cell lung cancer and other solid tumors

GV Scagliotti, S Novello - Cancer treatment reviews, 2012 - Elsevier
… hallmarks of cancer. The insulin-like growth factor (IGF) signaling system is one such
pathway, and plays a key role in the growth and development of non-small cell lung cancer (NSCLC…