Biomarkers predicting clinical outcome of epidermal growth factor receptor–targeted therapy in metastatic colorectal cancer

S Siena, A Sartore-Bianchi… - Journal of the …, 2009 - academic.oup.com
… and cetuximab that target the epidermal growth factor receptor (EGFR) have expanded the
… by immunostaining does not reliably predict clinical outcome of EGFR-targeted treatment has …

Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes

MF Rimawi, PB Shetty, HL Weiss… - … Journal of the …, 2010 - Wiley Online Library
… Epidermal growth factor receptor (EGFR) expression is associated with … Clinical and biological
features of EGFR‐positive and EGFR‐negative tumors were compared. Clinical outcomes

Association between HER-2/neu and Vascular Endothelial Growth Factor Expression Predicts Clinical Outcome in Primary Breast Cancer Patients

GE Konecny, YG Meng, M Untch, HJ Wang… - Clinical cancer …, 2004 - AACR
… Moreover, when looking for a potential biological concentration response effect between
VEGF expression levels and clinical outcome, we were able to demonstrate that absolute levels …

Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer

P Wikström, P Stattin, I Franck‐Lissbrant… - The …, 1998 - Wiley Online Library
BACKGROUND Prostate tumors express high levels of transforming growth factor‐β1 (TGF‐β1)
and seem to acquire resistance to its antiproliferative effects with tumor progression. …

Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an …

DM Jackman, VA Miller, LA Cioffredi, BY Yeap… - Clinical Cancer …, 2009 - AACR
Clinical outcomes were analyzed to look for differences based on EGFR and KRAS genotypes,
as well as clinical … receptor (EGFR) and KRAS mutations on clinical outcomes to EGFR–…

Gene therapy approach with an emphasis on growth factors: theoretical and clinical outcomes in neurodegenerative diseases

DGT Parambi, KS Alharbi, R Kumar, S Harilal… - Molecular …, 2022 - Springer
… Despite the many clinical trials conducted so far, data have shown disappointing outcomes.
The efforts done to improve outcomes, efficacy, and safety in the identification of targets in …

Impact of hormone receptor status on patterns of recurrence and clinical outcomes among patients with human epidermal growth factor-2-positive breast cancer in the …

I Vaz-Luis, RA Ottesen, ME Hughes, PK Marcom… - Breast Cancer …, 2012 - Springer
… on clinical trial data alone. We aimed to describe clinicopathological features, patterns of
recurrence and clinical outcomes of HER2-positive breast cancer according to HR status. …

[PDF][PDF] Transforming growth factor‐β gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

C Coulouarn, VM Factor, SS Thorgeirsson - Hepatology, 2008 - Wiley Online Library
… that showed significant differences in biological properties and clinical outcome (Fig. 5). Thus…
a positive hepatocyte growth factor/c-Met signature and the worst patient outcome. Here we …

The significance of placenta growth factor in angiogenesis and clinical outcome of human gastric cancer

CN Chen, FJ Hsieh, YM Cheng, WF Cheng, YN Su… - Cancer letters, 2004 - Elsevier
growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of
proangiogenic factors … (MVD), as well as clinical outcome in 79 patients with gastric cancer by …

Epidermal growth factor receptor polymorphisms and clinical outcomes in non-small-cell lung cancer patients treated with gefitinib

G Liu, S Gurubhagavatula, W Zhou, Z Wang… - The …, 2008 - nature.com
… clear relationship between protein expression and clinical outcomes in patients treated with
… each has been highly correlated with clinical outcomes. Evidence has been growing that …