Developing inhibitors of the epidermal growth factor receptor for cancer treatment
V Grunwald, M Hidalgo - Journal of the National Cancer Institute, 2003 - academic.oup.com
… factors such as vascular endothelial growth factor, interleukin 8, and basic fibroblast growth
factor; inhibition of those factors … vessel formation and the development of distant metastases …
factor; inhibition of those factors … vessel formation and the development of distant metastases …
Modulation of growth factor action: implications for the treatment of cardiovascular diseases
J Waltenberger - Circulation, 1997 - Am Heart Assoc
… indirect effects of growth factors because the expression of growth factors and their receptors
can be regulated by other growth factors (Table 2). The majority of growth factors, such as …
can be regulated by other growth factors (Table 2). The majority of growth factors, such as …
Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives
… of growth factor ligands. More specifically, when testing different growth factors on a series
of kinase-addicted cancer cell lines that are sensitive to specific TKIs, hepatocyte growth factor…
of kinase-addicted cancer cell lines that are sensitive to specific TKIs, hepatocyte growth factor…
A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor
F Ciardiello, G Tortora - Clinical Cancer Research, 2001 - AACR
… first growth factors to be discovered and is the prototype of a large family of closely related
growth factors… Among these growth factors, TGFα has been identified as a key modulator in the …
growth factors… Among these growth factors, TGFα has been identified as a key modulator in the …
Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities
H Modjtahedi, S Essapen - Anti-cancer drugs, 2009 - journals.lww.com
… of autocrine EGFR ligands (eg tumour growth factor-α, epiregulin), or development of skin
rash were suggested as indicators of response to treatment with the EGFR inhibitors [ 14,25–…
rash were suggested as indicators of response to treatment with the EGFR inhibitors [ 14,25–…
Epidermal growth factor and epidermal growth factor receptor: the Yin and Yang in the treatment of cutaneous wounds and cancer
RJ Bodnar - Advances in wound care, 2013 - liebertpub.com
… With the advent of growth factor inhibitors, their increasing use in the treatment of cancer
has led to an increased incidence in the development of a number of serious skin reactions. In …
has led to an increased incidence in the development of a number of serious skin reactions. In …
Growth factors and treatment of intervertebral disc degeneration
K Masuda, TR Oegema Jr, HS An - Spine, 2004 - journals.lww.com
… Finally, we will discuss the possibility of using growth factors as a treatment tool and the …
As the first quantitative study of in vivo growth factor treatment, we examined radiographic and …
As the first quantitative study of in vivo growth factor treatment, we examined radiographic and …
Therapeutic interventions for enhancing collateral development by administration of growth factors: basic principles, early results and potential hazards
SE Epstein, S Fuchs, YF Zhou, R Baffour… - Cardiovascular …, 2001 - academic.oup.com
… development. In the early 1990s it was first shown that basic fibroblast growth factor (bFGF)
and vascular endothelial growth factor (… are suggestive of a VEGF treatment effect, they are …
and vascular endothelial growth factor (… are suggestive of a VEGF treatment effect, they are …
Nerve growth factor: from the early discoveries to the potential clinical use
L Aloe, ML Rocco, P Bianchi, L Manni - Journal of translational medicine, 2012 - Springer
… development of neuropathic symptoms associated with, ie, diabetes, HIV infections or
chemotherapy, and point to the neurotrophin as a possible pharmacological tool in the treatment of …
chemotherapy, and point to the neurotrophin as a possible pharmacological tool in the treatment of …
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
J Mendelsohn, J Baselga - Journal of clinical oncology, 2003 - ascopubs.org
… production of angiogenic growth factors such as basic fibroblast growth factor, vascular
endothelial growth factor, and interleukin-8. 50 The decrease in angiogenic growth factors, in turn…
endothelial growth factor, and interleukin-8. 50 The decrease in angiogenic growth factors, in turn…
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