Exon and intron sequences, respectively, repress and activate splicing of a fibroblast growth factor receptor 2 alternative exon
F Del Gatto, R Breathnach - Molecular and cellular biology, 1995 - Taylor & Francis
… This inhibition can be overcome by mutating either the exon’s 5 or 3 splice site to make it
correspond more closely to the relevant consensus sequence. Two separate sequence …
correspond more closely to the relevant consensus sequence. Two separate sequence …
Efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 …
SJ Park, HT Kim, DH Lee, KP Kim, SW Kim, C Suh… - Lung cancer, 2012 - Elsevier
… an activating epidermal growth factor receptor (EGFR) … They received either erlotinib or
gefitinib once a day. Out of … tumors during their disease course, either whole brain radiotherapy or …
gefitinib once a day. Out of … tumors during their disease course, either whole brain radiotherapy or …
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
E Tischer, R Mitchell, T Hartman, M Silva… - Journal of Biological …, 1991 - Elsevier
… growth factor (VEGF) is an apparently endothelial cell-specific mitogen that is structurally
related to platelet-derived growth factor… gene is split among eight exons and that the various …
related to platelet-derived growth factor… gene is split among eight exons and that the various …
[HTML][HTML] … gefitinib and erlotinib treatment in non–small-cell lung cancer patients harboring an epidermal growth factor receptor mutation in either exon 19 or 21
SH Lim, JY Lee, JM Sun, JS Ahn, K Park… - Journal of Thoracic …, 2014 - Elsevier
… A total of 375 patients with recurrent or metastatic stage IIIB/IV NSCLC, who had either exon
19 deletion or the L858R mutation in exon 21, and had received either gefitinib (n = 228) or …
19 deletion or the L858R mutation in exon 21, and had received either gefitinib (n = 228) or …
Clinical course of patients with non–small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
… Seventy patients (24%) were found to have either EGFR exon 19 deletion or EGFR
L858R. The clinical characteristics of patients tested for EGFR mutations are listed in Table 1. …
L858R. The clinical characteristics of patients tested for EGFR mutations are listed in Table 1. …
Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non–small cell lung cancer patients treated with gefitinib or …
DM Jackman, BY Yeap, LV Sequist, N Lindeman… - Clinical Cancer …, 2006 - AACR
… The primary focus of this analysis is patients with either exon 19 deletions or L858R point
mutations. Table 1 shows the baseline characteristics of the patients found to have one of …
mutations. Table 1 shows the baseline characteristics of the patients found to have one of …
An intronic splicing silencer causes skipping of the IIIb exon of fibroblast growth factor receptor 2 through involvement of polypyrimidine tract binding protein
RP Carstens, EJ Wagner… - Molecular and cellular …, 2000 - Am Soc Microbiol
… IIIb and IIIc were transfected into DT3 and AT3 cells, we observed a predominant product
that consisted of either exon IIIb or exon IIIc spliced between the adenovirus upstream (U) …
that consisted of either exon IIIb or exon IIIc spliced between the adenovirus upstream (U) …
Comparison of clinical outcome of patients with non-small-cell lung cancer harbouring epidermal growth factor receptor exon 19 or exon 21 mutations
YW Won, JY Han, GK Lee, SY Park, KY Lim… - Journal of clinical …, 2011 - jcp.bmj.com
… To evaluate clinical differences between the two most common EGFR mutations, we
retrospectively analysed RR and survival of advanced NSCLC patients harbouring either the exon …
retrospectively analysed RR and survival of advanced NSCLC patients harbouring either the exon …
Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway
… in a 2:1 ratio to receive either 150 mg of erlotinib daily or a … 90% of these mutations occur at
exons 19 and 21 near the ATP … The most common mutations in the EGFR gene are an exon …
exons 19 and 21 near the ATP … The most common mutations in the EGFR gene are an exon …
hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc
DM Mauger, C Lin… - Molecular and cellular …, 2008 - Taylor & Francis
… growth factor receptor 2 exon IIIc. In cells that normally include this exon, we show that the
overexpression of either hnRNP H1 or hnRNP F resulted in the dramatic silencing of exon IIIc. …
overexpression of either hnRNP H1 or hnRNP F resulted in the dramatic silencing of exon IIIc. …
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- vascular endothelial growth factor
- epidermal growth factor receptor mutations
- fibroblast growth factor receptor
- cell lung cancer growth factor receptor
- growth factor family
- growth factor receptor tyrosine kinase inhibitors
- fibroblast growth factor exon choice
- lung cancer growth factor
- fibroblast growth factor exon sequences
- small cell lung cancer growth factor
- genomic organization growth factor
- cell differentiation growth factor
- alternative exon splicing growth factor
- growth factor receptor exon
- growth factor orphan exon
- growth factoreither exon