Erlotinib in cancer treatment
MA Bareschino, C Schettino, T Troiani, E Martinelli… - Annals of oncology, 2007 - Elsevier
… growth factor (EGF) belongs to a family of related peptides (EGF-like growth factor), which
include transforming growth factor o (TGFo… EGF-like growth factors bind to activate one or more …
include transforming growth factor o (TGFo… EGF-like growth factors bind to activate one or more …
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
DA Haas-Kogan, MD Prados, T Tihan… - Journal of the …, 2005 - academic.oup.com
… from tissue resected 68 days after the initiation of erlotinib treatment, after the patient was
off study and no longer treated with erlotinib. There was not sufficient tissue to complete all …
off study and no longer treated with erlotinib. There was not sufficient tissue to complete all …
[HTML][HTML] Clinical utility of epidermal growth factor receptor expression for selecting patients with advanced non-small cell lung cancer for treatment with erlotinib
GM Clark, DM Zborowski, JL Culbertson… - Journal of Thoracic …, 2006 - Elsevier
… Erlotinib (Tarceva®) has demonstrated a survival benefit in … erlotinib, epidermal growth
factor receptor (EGFR) protein expression may provide a basis for selecting patients for treatment …
factor receptor (EGFR) protein expression may provide a basis for selecting patients for treatment …
[HTML][HTML] Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review
R Feld, SS Sridhar, FA Shepherd, JA Mackay… - Journal of Thoracic …, 2006 - Elsevier
… cell carcinoma; erlotinib; gefitinib; and epidermal growth factor receptor were combined with
… cell lung; Iressa; gefitinib; ZD1839; Tarceva; erlotinib; OSI774; and EGFR-TK. These terms …
… cell lung; Iressa; gefitinib; ZD1839; Tarceva; erlotinib; OSI774; and EGFR-TK. These terms …
Current Knowledge and Future Directions of the Selective Epidermal Growth Factor Receptor Inhibitors Erlotinib (Tarceva®) and Gefitinib (Iressa®)
WS Siegel-Lakhai, JH Beijnen, JHM Schellens - The oncologist, 2005 - academic.oup.com
… Besides mutations in the EGFR gene that make the target sensitive to gefitinib and erlotinib
treatment, it has been shown that other mutations in the EGFR gene are associated with …
treatment, it has been shown that other mutations in the EGFR gene are associated with …
[HTML][HTML] Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial
JP Wang, CY Wu, YC Yeh, YM Shyr, YY Wu, CY Kuo… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… Most adverse events associated with erlotinib plus gemcitabine treatment in this study
were mild-to-moderate, consistent with previous studies [2-5]. Rash was more frequent with …
were mild-to-moderate, consistent with previous studies [2-5]. Rash was more frequent with …
[HTML][HTML] SELECT: a phase II trial of adjuvant erlotinib in patients with resected epidermal growth factor receptor–mutant non–small-cell lung cancer
NA Pennell, JW Neal, JE Chaft, CG Azzoli… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
… Recurrent cancer was noted in 40 patients, four while receiving erlotinib treatment and 36
after stopping erlotinib (Appendix Table A1, online only). The median time to recurrence after …
after stopping erlotinib (Appendix Table A1, online only). The median time to recurrence after …
Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer
Y Li, S Lam, JC Mak, C Zheng, JC Ho - Lung cancer, 2013 - Elsevier
… In this study, we investigated the effect of erlotinib treatment on autophagy in 4 NSCLC cell
lines with different EGFR mutation status, in order to understand the possible mechanisms …
lines with different EGFR mutation status, in order to understand the possible mechanisms …
Correlation between development of rash and efficacy in patients treated with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib in two large phase …
B Wacker, T Nagrani, J Weinberg, K Witt, G Clark… - Clinical Cancer …, 2007 - AACR
… of rash during treatment with the epidermal growth factor receptor inhibitor erlotinib and
improved … (single agent in non–small-cell lung cancer, n = 444 in erlotinib group and n = 229 in …
improved … (single agent in non–small-cell lung cancer, n = 444 in erlotinib group and n = 229 in …
Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva)
P Chinnaiyan, S Huang, G Vallabhaneni, E Armstrong… - Cancer research, 2005 - AACR
… Erlotinib (Tarceva) is an orally available HER1 (epidermal growth factor receptor, EGFR)
tyrosine kinase inhibitor advancing through clinical trials for the treatment of a range of human …
tyrosine kinase inhibitor advancing through clinical trials for the treatment of a range of human …
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