… α5 integrin subunit had a particulary important role. Latent forms of transforming growth factor
… cell adhesion, and this adhesion was, as for the angiopoietins, mediated by integrins (16). …

… indicate that integrin ligation is required for growth factor–induced … , integrins can directly
associate with growth factor receptors, thereby regulating the capacity of integrin/growth factor …

… expression of α 5 integrin is due to induction of autocrine negative transforming growth factor-β
(TGF-β) activity. MCF-7 breast cancer cells do not express either α 5 integrin or type II TGF…

… integrin interaction. We conclude that asTF, unlike flTF, does not affect angiogenesis via
PAR-dependent pathways but relies on integrin ligation… vascular endothelial growth factor (VEGF…

… of these same integrin α5β1 antagonists to impact growth factor-induced angiogenesis on the
… bFGF, antagonists of integrin α5β1 were applied directly to the growth factor-saturated filter …

… Members of the integrin family recognize a variety of spatially-restricted extracellular ligands.
Classically, ligation of integrins activates cytoplasmic signals in the integrin-expressing cell …

… which integrin ligation is the primum movens for proper activation of growth factor receptors,
thus undermining the dogma that cooperation between integrins and growth factor receptors …

… As a first step to examine the relationship between integrin ligation, β 3 phosphorylation
and VEGFR-2 activation, we monitored phosphorylation of β 3 at Tyr747 and Tyr759 in ECs …

… Integrins provide a physical link between the extracellular matrix and the cell cytoskeleton.
Integrin ligation … regulate cell survival and growth, cell differentiation and cell motility. Although …

… growth factor-induced motility of HT29-D4 cells was affected both by PKC and MAP kinase
cascade inhibitors. It thus appears that both integrin ligation … to the integrin and growth factor …