Growth factors for the treatment of ischemic brain injury (growth factor treatment)
A Larpthaveesarp, DM Ferriero, FF Gonzalez - Brain sciences, 2015 - mdpi.com
… (BDNF), and insulin-like growth factor (IGF-1), among others. … growth factors that should be
used to maximize both brain … for growth factor therapies in treating different causes of brain …
used to maximize both brain … for growth factor therapies in treating different causes of brain …
Transforming growth factor-β and ischemic brain injury
… cytokines and other growth factors may influence the outcome of brain cells during
neurodegenerative diseases. However, because of the pleiotropic actions of these factors, the use of …
neurodegenerative diseases. However, because of the pleiotropic actions of these factors, the use of …
Growth factors in ischemic stroke
S Lanfranconi, F Locatelli, S Corti… - Journal of cellular …, 2011 - Wiley Online Library
… Both hOECs/ONFs and endogenous homing stem cells enhanced neuroplasticity in the
rat and mouse ischemic brain. The up-regulation of SDF-1α and the enhancement of CXCR4 …
rat and mouse ischemic brain. The up-regulation of SDF-1α and the enhancement of CXCR4 …
Transforming growth factor-β: a neuroprotective factor in cerebral ischemia
KM Dhandapani, DW Brann - Cell biochemistry and biophysics, 2003 - Springer
… growth factor-βs (TGF-βs) represent a large family of growth … growth factor-β antagonist
unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain …
unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain …
Effects of vascular endothelial growth factor in ischemic stroke
Y Ma, A Zechariah, Y Qu… - Journal of neuroscience …, 2012 - Wiley Online Library
… angiogenic growth factors expressed in the ischemic brain, vascular endothelial growth factor
(… Below we summarize existing knowledge on the effects of VEGF in the ischemic brain. A …
(… Below we summarize existing knowledge on the effects of VEGF in the ischemic brain. A …
Insulin-like growth factor-1 and post-ischemic brain injury
J Guan, L Bennet, PD Gluckman, AJ Gunn - Progress in neurobiology, 2003 - Elsevier
Insulin-like growth factor-1 (IGF-1) is a naturally occurring neurotrophic factor that plays an
important role in promoting cell proliferation and differentiation during normal brain …
important role in promoting cell proliferation and differentiation during normal brain …
Insulin-like growth factors in the response to cerebral ischemia
WH Lee, JA Clemens, CA Bondy - Molecular and Cellular Neuroscience, 1992 - Elsevier
… IGFBP-1 mRNA was not detected in the normal or ischemic brain at any point in this study
(data not shown). IGF-I mRNA was highly abundant and widely distributed throughout the …
(data not shown). IGF-I mRNA was highly abundant and widely distributed throughout the …
Vascular endothelial growth factor: an attractive target in the treatment of hypoxic/ischemic brain injury
H Guo, H Zhou, J Lu, Y Qu, D Yu… - Neural regeneration …, 2016 - journals.lww.com
… endothelial growth factor signaling. In this review, we focus on the role of the vascular
endothelial growth factor signaling pathway in the response to hypoxic/ischemic brain injury, and …
endothelial growth factor signaling pathway in the response to hypoxic/ischemic brain injury, and …
Ischemic rat brain extracts induce human marrow stromal cell growth factor production
X Chen, Y Li, L Wang, M Katakowski, L Zhang… - …, 2002 - Wiley Online Library
… and angiogenic growth factors increased in a post‐ischemia time‐… of growth and trophic
factors may be the key to the benefit provided by transplanted hMSCs in the ischemic brain. …
factors may be the key to the benefit provided by transplanted hMSCs in the ischemic brain. …
Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis
PS Manoonkitiwongsa, RL Schultz… - Journal of Cerebral …, 2004 - journals.sagepub.com
… and did not damage neurons of normal brains. In contrast… ischemic brains and damaged
neurons of normal brains. These findings suggest that in vivo neuroprotection of ischemic brains …
neurons of normal brains. These findings suggest that in vivo neuroprotection of ischemic brains …
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