The biology of epidermal growth factor receptor in lung cancer
GV Scagliotti, G Selvaggi, S Novello, FR Hirsch - Clinical Cancer Research, 2004 - AACR
The prognostic significance of epidermal growth factor receptor (EGFR) expression in lung
cancer and, more importantly, its ability to predict response to anti-EGFR therapies, are …
cancer and, more importantly, its ability to predict response to anti-EGFR therapies, are …
Epidermal growth factor receptor mutations in lung cancer
SV Sharma, DW Bell, J Settleman, DA Haber - Nature Reviews Cancer, 2007 - nature.com
… that target the epidermal growth factor receptor (EGFR) provide important insights for new
lung cancer therapies, as well as for the broader field of targeted cancer therapies. We review …
lung cancer therapies, as well as for the broader field of targeted cancer therapies. We review …
Epidermal growth factor receptor family in lung cancer and premalignancy
WA Franklin, R Veve, FR Hirsch, BA Helfrich… - Seminars in …, 2002 - Elsevier
… proteins, particularly overexpression of epidermal growth factor receptor (EGFR) family …
EGF and transforming growth factor alpha. Epidermal growth factor receptor overexpression is …
EGF and transforming growth factor alpha. Epidermal growth factor receptor overexpression is …
[HTML][HTML] Screening for epidermal growth factor receptor mutations in lung cancer
… growth factor receptor (EGFR), PI3K, BRAF, and K-ras genes are generally nonoverlapping
and identifiable in approximately 40% of non–small-cell lung cancers… small-cell lung cancers. …
and identifiable in approximately 40% of non–small-cell lung cancers… small-cell lung cancers. …
Epidermal growth factor receptors in non-small cell lung cancer
D Veale, T Ashcroft, C Marsh, GJ Gibson… - … journal of cancer, 1987 - nature.com
… Our results suggest thatepidermal growth factor receptor may play a part in the genesis or
spread of lung cancers. This is the third common primary carcinoma in which we have found a …
spread of lung cancers. This is the third common primary carcinoma in which we have found a …
[HTML][HTML] Epidermal growth factor receptor (EGFR) in lung cancer: an overview and update
G Bethune, D Bethune, N Ridgway… - Journal of thoracic …, 2010 - ncbi.nlm.nih.gov
… Mutations in epidermal growth factor receptor have been discovered in association with
some lung cancers. Lung adenocarcinomas with mutated epidermal growth …
some lung cancers. Lung adenocarcinomas with mutated epidermal growth …
[HTML][HTML] Epidermal growth factor receptor inhibition in lung cancer: status 2012
… Lung cancer is the most common cause of cancer deaths. … However, with the understanding
of lung cancer biology, and … patients with non–small-cell lung cancer (NSCLC). Epidermal …
of lung cancer biology, and … patients with non–small-cell lung cancer (NSCLC). Epidermal …
Targeting the epidermal growth factor receptor in non-small cell lung cancer
RS Herbst, PA Bunn Jr - Clinical cancer research, 2003 - AACR
… growth seen with EGFR-TK inhibition is also accompanied by decreases in vascular endothelial
growth factor (VEGF), basic fibroblast growth factor (… inhibit tumor growth by interfering …
growth factor (VEGF), basic fibroblast growth factor (… inhibit tumor growth by interfering …
[HTML][HTML] Role of epidermal growth factor receptor in lung cancer and targeted therapies
TC Liu, X Jin, Y Wang, K Wang - American Journal of Cancer …, 2017 - ncbi.nlm.nih.gov
… In the current review, we propose to illustrate the role of EGFR group of growth factors in lung
cancer progression and metastasis. We will particularly emphasize upon the impact of well-…
cancer progression and metastasis. We will particularly emphasize upon the impact of well-…
Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies
FR Hirsch, GV Scagliotti, CJ Langer, M Varella-Garcia… - Lung cancer, 2003 - Elsevier
… in patients with lung cancer [4], [5… lung cancer. The gene mechanisms for the protein
expression will be discussed, and for the HER2, differences between lung cancer and breast cancer …
expression will be discussed, and for the HER2, differences between lung cancer and breast cancer …
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