Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells

K Kurokawa, T Nakamura, K Aoki… - Biochemical Society …, 2005 - portlandpress.com
… In contrast, on epidermal growth factor stimulation, RhoA … Notably, RhoA activity persisted
at the tip of growth factor-… control cytoskeletal changes and that the basic mechanism of …

Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation

Y Saito, J Haendeler, Y Hojo… - Molecular and cellular …, 2001 - Am Soc Microbiol
… Normal sheep IgG was used as a negative control for anti-EGFR (lane 5). Immunoblotting …
Normal rabbit IgG was used as a negative control for anti-PDGFβR. Immunoblotting was …

Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphatase

L Mahimainathan, GG Choudhury - Journal of Biological Chemistry, 2004 - ASBMB
… As a potential mechanism, we show that PTEN inhibits PDGF-induced protein tyrosine …
PTEN is physically associated with platelet-derived growth factor (PDGF) receptor and that PDGF …

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

A Machnik, W Neuhofer, J Jantsch, A Dahlmann… - Nature medicine, 2009 - nature.com
… These results suggest that a negative feedback mechanism controls VEGF-C expression in
the … These data suggest that MPS cells are centrally involved in the homeostatic control of …

Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism

S Schultz-Cherry, JE Murphy-Ullrich - The Journal of cell biology, 1993 - rupress.org
Thrombospondin (TSP) forms specific complexes with transforming growth factor-beta (TGF-beta)
in the alpha granule releasate of platelets and these TSP-TGF-beta complexes inhibit …

Fibroblast growth factor receptor-1 (FGFR1) nuclear dynamics reveal a novel mechanism in transcription control

SM Dunham-Ems, YW Lee… - Molecular biology of …, 2009 - Am Soc Cell Biol
… ), has been shown to control cell development (Stachowiak et al., 2007). In INFS, activation
of cell surface neurotransmitter, hormonal or growth factor receptors, and their intracellular …

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth

O Melnyk, MA Shuman, KJ Kim - Cancer research, 1996 - AACR
… ±71 for lung controls and 665 ±63 for brain controls). In … of comparable size in untreated
control animals to have an … extent of metastasesin untreated control animals with comparably …

The effect of finasteride on the expression of vascular endothelial growth factor and microvessel density: a possible mechanism for decreased prostatic bleeding in …

G Pareek, M Shevchuk, NA Armenakas… - The Journal of …, 2003 - auajournals.org
… In view of our prior studies correlating decreased microvessel density in finasteride treated
prostates, 7 we postulate that the potential mechanism of finasteride in controlling prostatic …

[HTML][HTML] Mechanism of sustained release of vascular endothelial growth factor in accelerating experimental diabetic healing

H Brem, A Kodra, MS Golinko, H Entero… - Journal of investigative …, 2009 - Elsevier
growth factor, which was used as a positive control because it is a potent stimulator of
keratinocyte migration and proliferation, migrated significantly faster than untreated, control cells (…

Growth factor regulation of cell growth and proliferation in the nervous system: a new intracrine nuclear mechanism

MK Stachowiak, J Moffett, P Maher, J Tucholski… - Molecular …, 1997 - Springer
mechanism of growth-factor action in the nervous system whereby fibroblast growth factor-2
(… serve as a novel mechanism controlling growth and proliferation of glial and neuronal cells. …