… dependent protein kinase, protein kinase A. Increases in cellular cAMP levels inhibit growth
factor-induced proliferation of vascular smooth muscle cells. cAMP-activates protein kinase A…

… Protein kinase B (PKB) is a member of the second-mesberiger regulated … of protein kinases
implicated lm signalling downstream of growth factor and insulin receptor tyrosine kinases …

… Nerve growth factor (NGF) … two protein kinases by >20-fold within minutes8, both strikingly
similar to MAPKs. They are inactivated by either protein-tyrosine phosphatases or the protein-…

… protein kinase induced by either tumor promoting phorbol esters, platelet-derived growth
factor, or basic fibroblast growth factor, but … protein kinases that are essential for growth factor …

… moters appear to be mediated by a protein kinase, which is dependent on Ca2+, … protein
itself possesses protein kinase activity with specificity for tyrosine residues in substrate proteins …

… membrane preparations for protein kinase activity and responsiveness to EGF. In preliminary
experiments, it was found that over 50% ofthe endogenous basal kinase activity could be …

… growth factor receptor and protein kinase C modulation of MAP kinases, RSKs, and Raf-1. …
EGF and acidic FGF receptors, and by protein kinase C (PKC). Expression of activated ras, but …

… Blocking the mitogen-activated protein kinase pathway with the specific mitogen-activated
protein kinase/extracellular-response kinase kinase inhibitor PD098059 (10 −5 M) inhibited …

… protein kinases (MAPKs) (Erkl and Erk2) are central components of a growth factorstimulated
protein kinase … kinases such as the platelet-derived growth factor (PDGF), epidermal …

… multifunctional mediator of growth factor-induced survival (21–23), we hypothesized that
enhanced cell survival may be one of the biological consequences of PI3-kinase/Akt activation …