… Upon investigation of the insulin-like growth factor (IGF) pathway, we found the IGF2BP3/IMP3
transcript and protein to be up-regulated in GBMs but not in lower grade astrocytomas (p …

… Recent evidence indicates that the epidermal growth factor (EGF) receptor mediates a …
-activated protein (MAP) kinase. However, it is unclear whether the intrinsic tyrosine kinase activity …

… Components of the mitogen-activated protein kinase (MAP kinase) signaling pathway,
including Ras, Raf, and MAP kinase, are necessary for nerve growth factor (NGF)-induced neurite …

… ); therefore, we also tested the effects of bisindolylmaleimide, a protein kinase C blocker,
on VEGF-stimulated proliferation and Raf-1 kinase activation. Neither bisindolylmaleimide nor …

… nerve growth factor (NGF) may be mediated by changes in protein phosphorylation. We have
identified a protein kinase … of pig brain microtubule-associated protein (MAP)-2 in vitro. This …

… Ionizing radiation, but not stimulation with epidermal growth factor (EGF), … growth factors
bind to and activate EGFR. In addition to EGF these factors include transforming growth factor…

… , slightly in response to epidermal growth factor, but not to … these agents on the activation of
protein kinase C in a cell-free … , 80,000 protein might be a useful indicator of protein kinase C …

… in protein kinase C activation and elevated eNOS expression, whereas inhibition of protein
kinase … KDR receptor tyrosine kinase and a downstream protein kinase C signaling pathway. …

… of key kinase cascades to growth factors, thereby priming cells for stimulation by latent growth
… breast cancer cell growth switches from steroid hormone to growth factor dependence. …

… Protein kinase B (PKB) is a member of the second messenger subfamily of protein
kinases. … -terminal pleckstrin homology domain, a central kinase domain, and a carboxy-terminal …