… growth factor receptor (EGFR) signaling inhibition. The most clinically advanced approach to
EGFR inhibition … use of small molecule tyrosine kinase inhibitors (TKIs) directed against the …

… most well-characterized growth factor receptor systems. In the … EGFR is the prototype of the
type-I growth factor receptor (… The binding of growth factors (eg EGF, tumour growth factor-α…

Novel therapeutic agents that target the epidermal growth factor receptor (EGFR) constitute
an important addition to the therapeutic armamentarium for the treatment of metastatic …

… Similar results might be expected from the combination of an epidermal growth factor receptor
(EGFR) TKI and an anti-IGF1R monoclonal antibody. Preclinical data have modeled the …

… Epidermal growth factor receptor (EGFR) inhibitors are associated with unique and dramatic
… of common dermatologic adverse reactions among EGFR inhibitors, focusing mainly on skin …

Novel therapeutic agents targeting the epidermal growth factor receptor (EGFR) have improved
outcomes for a subgroup of patients with colorectal, lung, head and neck, and pancreatic …

The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling pathway
plays a fundamental role in many physiologic processes, including embryogenesis, adult …

… Epidermal growth factor receptor (EGFR) is an intriguing target in high-grade gliomas
because it is frequently overexpressed due to amplification of the EGFR gene. Gefitinib and …

… The use of epidermal growth factor receptor (EGFR) inhibitors in several epithelial tumors …
of patients receiving EGFR inhibitors. The skin toxicity is related to the inhibition of EGFR in the …

… vascular endothelial growth factor Epidermal growth factor receptor (EGFR) inhibitors are
being used more frequently to treat advanced malignancies. Their chemotherapeutic potential …