Dermatologic adverse events associated with selective fibroblast growth factor receptor inhibitors: overview, prevention, and management guidelines

ME Lacouture, V Sibaud, MJ Anadkat… - The …, 2021 - academic.oup.com
… Schematic representation of dermatologic adverse events associated with fibroblast growth
factor receptor inhibition. Suggested dose modifications for dermatologic adverse events: …

Noncovalent mutant selective epidermal growth factor receptor inhibitors: a lead optimization case study

R Heald, KK Bowman, MC Bryan… - Journal of medicinal …, 2015 - ACS Publications
Because of their increased activity against activating mutants, first-generation epidermal
growth factor receptor (EGFR) kinase inhibitors have had remarkable success in treating non-…

Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory …

JW Clark, JP Eder, D Ryan, C Lathia, HJ Lenz - Clinical Cancer Research, 2005 - AACR
Purpose: BAY 43-9006, a novel multikinase inhibitor, prevents tumor growth by combining
two antitumor activities: inhibition of both tumor cell proliferation and tumor angiogenesis. This …

[PDF][PDF] Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma

BC Fuchs, Y Hoshida, T Fujii, L Wei, S Yamada… - …, 2014 - Wiley Online Library
factor for HCC is cirrhosis and several lines of evidence implicate epidermal growth factor
(… We therefore examined the effects of the EGF receptor (EGFR) inhibitor erlotinib on liver …

Epidermal growth factor receptor inhibitors: a moving target?

SE Bates, T Fojo - Clinical Cancer Research, 2005 - AACR
… first agents targeting the epidermal growth factor receptor (EGFR) … that antibodies inhibiting
the pathway could retard cell growth, … in the tumors rather than a failure of receptor inhibition. …

The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) …

ME Lacouture, SE Lai - British Journal of Dermatology, 2006 - academic.oup.com
… of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) …
the small molecule epidermal growth factor receptor (EGFR) inhibitor erlotinib (upper panel)…

Dermatological side effects of epidermal growth factor receptor inhibitors:'PRIDE'complex

B Madke, P Gole, P Kumar… - Indian journal of …, 2014 - journals.lww.com
… Epidermal growth factor receptor (EGFR) inhibitor therapy has become the standard treatment
for … is a marker of effectiveness of therapy with epidermal growth factor receptor inhibitor. …

Epidermal growth factor receptor tyrosine kinase inhibitors as potential cancer chemopreventives.

GJ Kelloff, JR Fay, VE Steele, RA Lubet… - … , biomarkers & prevention …, 1996 - AACR
growth factor receptor (EGFR) has been selected as a potential target for chemoprevention.
Because growth factor networks are redundant, selective inhibition … EGFR inhibitors include …

Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan–human epidermal growth factor receptor inhibitor, versus erlotinib in patients with …

SS Ramalingam, F Blackhall, M Krzakowski… - Journal of Clinical …, 2012 - ascopubs.org
… These reversible tyrosine kinase inhibitors (TKIs) selectively target HER1 (human epidermal
growth factor receptor [EGFR, ErbB1]), one of the four HER family receptors (EGFR, ErbB1, …

Density of Demodex folliculorum in Patients Receiving Epidermal Growth Factor Receptor Inhibitors

PA Gerber, G Kukova, BA Buhren, B Homey - Dermatology, 2011 - karger.com
Background: Rosacea-like papulopustular eruptions (rash) are considered the most frequent
toxicities associated with the use of inhibitors of the epidermal growth factor receptor (EGFR…