… receiving EGFR inhibitors. The skin toxicity is related to the inhibition of EGFR in the skin,
which … Although rarely life-threatening, skin toxicity may cause significant physical and psycho-…

The last few years, new therapies targeting the epidermal growth factor receptor (EGFR)
have shown their efficacy in the treatment of several types of cancer. Monoclonal antibodies …

… Epidermal growth factor receptor (EGFR) inhibitors are … among EGFR inhibitors, focusing
mainly on skin toxicity, as well … adverse effect was a mild skin toxicity characterized by a sterile …

… mechanism of skin toxicity and the relationship between skin toxicity and … inhibitors. Here,
we focus on the mechanism of skin toxicity and fatal skin toxicity caused by EGFR inhibitors …

… growth factor receptor inhibitor (EGFRI) induced skin toxicity has a prognostic value suggesting
skin toxicity … for successful epidermal growth factor receptor (EGFR) inhibition, improved …

… the effectiveness of various therapeutic agents for the treatment and prevention of dermatologie
effects secondary to epidermal growth factor receptor inhibitor (EGFRI) administration. …

… growth factor receptor inhibitors (… toxicities affecting the skin and adnexal structures, and
mucosal surfaces that affect the majority of treated patients. Significant dermatologic toxicities …

… rate for patients on the cetuximab arm who developed skin toxicity was 33%, compared
with 7% for patients who did not develop skin toxicity [47]. This difference was not statistically …

… In short, patients may be responding to a constellation of toxicities as opposed to a focused
skin toxicity like PPR, which is aligned most closely with the aims of the Skindex-16 as a …

… response, especially for the epidermal growth factor receptor inhibitors (EGFRI). Optimum
… of skin toxicity from targeted chemotherapy, giving emphasis on the single-targeted inhibitor…