Epidermal growth factor receptor mutations in lung cancer

SV Sharma, DW Bell, J Settleman, DA Haber - Nature Reviews Cancer, 2007 - nature.com
The development and clinical application of inhibitors that target the epidermal growth factor
receptor (EGFR) provide important insights for new lung cancer therapies, as well as for the …

Screening for epidermal growth factor receptor mutations in lung cancer

R Rosell, T Moran, C Queralt, R Porta… - … England Journal of …, 2009 - Mass Medical Soc
… Activating mutations in the epidermal growth factor receptor gene (EGFR) confer …
EGFR mutations in such patients and analyzed the association between the mutations and …

[HTML][HTML] Epidermal growth factor receptor mutations in lung adenocarcinoma

MD Siegelin, AC Borczuk - Laboratory investigation, 2014 - Elsevier
… therapeutics, the discovery of mutations in epidermal growth factor receptor (EGFR) in 15–20…
responses despite presence of activating EGFR mutations. epidermal growth factor receptor

Clinical spectrum of fibroblast growth factor receptor mutations

MR Passos‐Bueno, WR Wilcox, EW Jabs… - … mutation, 1999 - Wiley Online Library
… entities, are caused by mutations in one of three fibroblast growth factor receptor genes (FGFR1,
FGFR2, and FGFR3). The present review list all mutations described to date in these …

Diversity and Frequency of Epidermal Growth Factor Receptor Mutations in Human Glioblastomas

L Frederick, XY Wang, G Eley, CD James - Cancer research, 2000 - AACR
… Several types of epidermal growth factor receptor (EGFR)gene mutations have been …
diversity of EGFR mutations in glioblastomas and to determine whether gene mutation is inevitably …

Epidermal growth factor receptor mutations in small cell lung cancer

A Tatematsu, J Shimizu, Y Murakami, Y Horio… - Clinical Cancer …, 2008 - AACR
growth factor receptor (EGFR) mutations are prevalent in female nonsmokers. However,
EGFR mutations … In this study, we first examined a large series of SCLCs to address mutation

Mutations and response to epidermal growth factor receptor inhibitors

P Laurent-Puig, A Lievre, H Blons - Clinical cancer research, 2009 - AACR
… agents targeting the epidermal growth factor receptor (EGFR) … , and frequent mutations
involving either the receptor itself or … The epidermal growth factor receptor (EGFR), a member of …

Epidermal growth factor receptor mutations in non–small-cell lung cancer: Implications for treatment and tumor biology

PA Jänne, JA Engelman, BE Johnson - Journal of clinical oncology, 2005 - ascopubs.org
… Summary of epidermal growth factor receptor (EGFR) mutations. The different domains of …
and frequencies of the different EGFR mutations. The shown mutations are those identified in …

Epidermal growth factor receptor mutations

EM McLoughlin, RD Gentzler - Thoracic surgery clinics, 2020 - thoracic.theclinics.com
… The discovery of the epidermal growth factor receptor (EGFR) and development of targeted
… EGFR belongs to the HER/ErbB family of growth factor receptors. These receptors consist of …

Epidermal growth factor receptor mutations in patients with non–small cell lung cancer

BE Johnson, PA Jänne - Cancer research, 2005 - AACR
… since mutations of the tyrosine kinase domain of the epidermal growth factor receptor (EGFR…
insight into the biological impact of EGFR mutations in cell culture experiments and in …