… Mutations of epidermal growth factor receptor in the current study. Numbers in parentheses
… mutation. Exons 18, 19, 21, and 23 were analyzed in the current study. (*) Novel mutations …

… Somatic mutations within the epidermal growth factor receptor (EGFR) kinase domain are …
difficult to assess the direct consequences of these mutations on EGFR enzyme function, we …

… responses to treatment with the epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors gefitinib and erlotinib have somatic mutations in the EGFR tyrosine kinase domain. …

Fibroblast-growth-factor receptors (FGFRs), members of the tyrosine-kinase receptor family,
play a crucial role in signal transduction and development. Recently, unique mutations in …

… The pathology of a male smoker with epidermal growth factor receptor mutation-positive
small cell lung cancer (SCLC). A, Tissue from an echo-guided lung biopsy. Under hematoxylin …

Background Afatinib is an irreversible ErbB-family blocker with preclinical activity in non-small-cell
lung cancer (NSCLC) with EGFR mutations. We aimed to assess the efficacy of …

… Most patients with non-small cell lung cancer (NSCLC) harboring common epidermal growth
factor receptor (EGFR) mutations, such as deletions in exon 19 or the L858R mutation in …

… In particular, epidermal growth factor receptor ( EGFR ) mutations … mutations and the new
lung adenocarcinoma classification schema are unclear. The discovery of activating mutations …

Purpose To retrospectively identify quantitative computed tomographic (CT) features that
correlate with epidermal growth factor receptor (EGFR) mutation in surgically resected lung …

… kinase domain of the epidermal growth factor receptor (EGFR), … likely to harbour mutations
of the receptor kinase domain, … Other EGFR kinase domain mutations have been found to …