The solution structure of human epidermal growth factor

RM Cooke, AJ Wilkinson, M Baron, A Pastore… - Nature, 1987 - nature.com
… transforming growth factors (TGF-… structure of EGF by diffraction methods have not yet
succeeded because of difficulties with crystallization. We report here a three-dimensional structure

The solution structures of epidermal growth factor and transforming growth factor alpha

ID Campbell, RM Cooke, M Baron, TS Harvey… - Progress in growth factor …, 1989 - Elsevier
… we have studied the solution structures of human … solution structures of small proteins (less
than approximately 150 residues) to be determined. We describe here the solution structures

Human epidermal growth factor: high resolution solution structure and comparison with human transforming growth factor α

U Hommel, TS Harvey, PC Driscoll… - Journal of molecular …, 1992 - Elsevier
solution structure of the 53 amino acid peptide hormone, human epidermal growth factor (…
Dynamical simulated annealing methods using the program XPLOR were used for structure

Solution structure of the heparin-binding domain of vascular endothelial growth factor

WJ Fairbrother, MA Champe, HW Christinger, BA Keyt… - Structure, 1998 - cell.com
… We report here the determination of the solution structure of the 55-residue heparin-binding
domain of VEGF 165 , using data from both homonuclear and heteronuclear NMR …

Transforming Growth Factor β1:  Three-Dimensional Structure in Solution and Comparison with the X-ray Structure of Transforming Growth Factor β2,

AP Hinck, SJ Archer, SW Qian, AB Roberts… - Biochemistry, 1996 - ACS Publications
solution structure of human transforming growth factor β1 (TGF-β1… of a mammalian protein
structure that has been solved by … The solution structure of the 25 kDa disulfide-linked TGF-β1 …

Solution structure and dynamics of epidermal growth factor and transforming growth factor alpha.

SJ Prestrelski, T Arakawa, CS Wu, KD O'Neal… - Journal of Biological …, 1992 - ASBMB
structure of transforming growth factor a (TGF-a) is very similar to that of epidermal growth
factor (… proteins, in particular in the ,&sheet structure. A large difference was observed with CD …

[HTML][HTML] Solution structure of midkine, a new heparin‐binding growth factor

W Iwasaki, K Nagata, H Hatanaka, T Inui… - The EMBO …, 1997 - embopress.org
… The solution structures of the two domains were determined by NMR. Both domains consist
of three antiparallel β‐strands, but the C‐terminal domain has a long flexible hairpin loop …

The solution structure of human transforming growth factor α

TS Harvey, AJ Wilkinson, MJ Tappin… - European journal of …, 1991 - Wiley Online Library
structure (Kline et al., 1990). Knowledge and comparison of the structures of these growth
factors … In this paper we further describe the solution structure of TGFa as investigated by a …

Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders

AK Downing, V Knott, JM Werner, CM Cardy… - Cell, 1996 - cell.com
… Here we present a novel structure of a covalently linked pair of cbEGF domains. We show
that in solution, the thirty-second and thirty-third cbEGF domains from human fibrillin-1 are …

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study

RM Cooke, TS Harvey, ID Campbell - Biochemistry, 1991 - ACS Publications
… of detailed information concerning the tertiary structures of IGFs. As part of a project …
structure-function relationships in protein growth factors, we have examined the solution structure of …