Growth factors, matrices, and forces combine and control stem cells

DE Discher, DJ Mooney, PW Zandstra - Science, 2009 - science.org
Growth factors added to culture or secreted by stem cells and nearby niche cells are often
potent in their effects on cell … for stem cell trafficking, continue to be clarified, but growth factor– …

[HTML][HTML] Transforming growth factor-β in stem cells and tissue homeostasis

X Xu, L Zheng, Q Yuan, G Zhen, JL Crane, X Zhou… - Bone research, 2018 - nature.com
… TGF-β 1–3 are unique multi-functional growth factors that are … -β in maintaining stem cells
and tissue homeostasis have not … the recruitment of stem/progenitor cell participation in tissue …

[HTML][HTML] Making a tooth: growth factors, transcription factors, and stem cells

YD Zhang, Z Chen, YQ Song, C Liu, YP Chen - Cell research, 2005 - nature.com
… These growth factors function synergistically and/or … Growth factor functions through binding
to its specific cell … the nucleus where latent transcription factors are activated, and eventually …

Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells

M Schuldiner, O Yanuka… - Proceedings of the …, 2000 - National Acad Sciences
… directed differentiation of human ES cells, we analyzed the effects of eight different growth
factors on embryonic cells in culture. By using assays for 24 cell-specific molecular markers, …

Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation

I Kratchmarova, B Blagoev, M Haack-Sorensen… - Science, 2005 - science.org
… To study the effects of growth factors on hMSC, we first tested the effects of EGF, PDGF,
fibroblast growth factor (FGF), and nerve growth factor (NGF) on cellular responses. Using …

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor

E Cattaneo, R McKay - Nature, 1990 - nature.com
… NERVE growth factor plays an important part in neuron-target interactions in the late …
growth factor controls the proliferation of neuronal precursors in a defined culture system of cells

Hepatocyte growth factor effects on mesenchymal stem cells: proliferation, migration, and differentiation

G Forte, M Minieri, P Cossa, D Antenucci, M Sala… - Stem …, 2006 - academic.oup.com
cell turnover, substitute injured cells, and repair tissue architecture. In this context, a major
challenge is represented by the identification of growth factors that … for future stem cell–based …

Transforming growth factor-β signaling in stem cells and cancer

L Mishra, R Derynck, B Mishra - Science, 2005 - science.org
… and tumor suppression, and they help define the selection of cellstem cells and in the
differentiation of neural, hematopoietic, mesenchymal, and gastrointestinal epithelial stem cells

Basic fibroblast growth factor controls migration in human mesenchymal stem cells

A Schmidt, D Ladage, T Schinköthe, U Klausmann… - Stem …, 2006 - academic.oup.com
… presence or absence of basic fibroblast growth factor (bFGF), erythropoietin, interleukin‐6,
stromal cell‐derived factor‐β, and vascular endothelial growth factor. bFGF in particular was …

Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2

Y Arsenijevic, S Weiss, B Schneider… - Journal of …, 2001 - Soc Neuroscience
stem cells (NSCs), when stimulated with epidermal growth factor (EGF) or fibroblast growth
factor-2 … We postulated that the early appearance of insulin-like growth factor (IGF-I) receptors …