Pathways mediating resistance to vascular endothelial growth factor–targeted therapy
LM Ellis, DJ Hicklin - Clinical cancer research, 2008 - AACR
… Vascular endothelial growth factor (VEGF)–targeted therapy … not respond to VEGF-targeted
therapy when used as a single … of benefit from VEGF-targeted therapy can be relatively short …
therapy when used as a single … of benefit from VEGF-targeted therapy can be relatively short …
Biology and clinical development of vascular endothelial growth factor–targeted therapy in renal cell carcinoma
BI Rini, EJ Small - Journal of Clinical Oncology, 2005 - ascopubs.org
… A growing understanding of the underlying biology of RCC has identified vascular endothelial
growth factor (VEGF) as a logical therapeutic target. Therapy directed against the biologic …
growth factor (VEGF) as a logical therapeutic target. Therapy directed against the biologic …
Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care
D Bose, F Meric-Bernstam, W Hofstetter… - The lancet …, 2010 - thelancet.com
… endothelial growth factor (VEGF) targeted therapy, … -targeted therapies, and their effect
on perioperative wound complications. Surgery in patients receiving VEGF-targeted therapies …
on perioperative wound complications. Surgery in patients receiving VEGF-targeted therapies …
Vascular endothelial growth factor–targeted therapy in renal cell carcinoma: current status and future directions
BI Rini - Clinical Cancer Research, 2007 - AACR
… associated with expression of vascular endothelial growth factor (VEGF). Recently, VEGF-targeted
therapies have been identified as a promising therapeutic approach. Three agents …
therapies have been identified as a promising therapeutic approach. Three agents …
VEGF-targeted therapy: therapeutic potential and recent advances
LS Rosen - The oncologist, 2005 - academic.oup.com
… Recent advances in the development of targeted therapies for the treatment of cancer have
… The VEGF family of molecules currently consists of six growth factors, including VEGF-A, …
… The VEGF family of molecules currently consists of six growth factors, including VEGF-A, …
The epidermal growth factor receptor pathway: a model for targeted therapy
M Scaltriti, J Baselga - Clinical cancer research, 2006 - AACR
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase receptor that is
frequently expressed in epithelial tumors. The EGFR was the first receptor to be proposed as a …
frequently expressed in epithelial tumors. The EGFR was the first receptor to be proposed as a …
Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor–targeted therapy
… endothelial growth factor (VEGF)–targeted therapy in … metastatic RCC respond to VEGF-targeted
therapy. On the basis of … received VEGF-targeted therapy were retrospectively identified, …
therapy. On the basis of … received VEGF-targeted therapy were retrospectively identified, …
Vascular endothelial growth factor‐targeted therapy in metastatic renal cell carcinoma
BI Rini - Cancer, 2009 - Wiley Online Library
… received sunitinib and other active, targeted therapy on progression, likely under powering
this … controls support the finding that targeted therapy has meaningfully extended the lives of …
this … controls support the finding that targeted therapy has meaningfully extended the lives of …
Clinical factors associated with outcome in patients with metastatic clear‐cell renal cell carcinoma treated with vascular endothelial growth factor‐targeted therapy
TK Choueiri, JA Garcia, P Elson… - … Journal of the …, 2007 - Wiley Online Library
… Five independent prognostic factors for predicting PFS were identified and were used to …
RCC who received VEGF-targeted therapies into 3 risk groups. These prognostic factors can be …
RCC who received VEGF-targeted therapies into 3 risk groups. These prognostic factors can be …
The impact of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor targeted therapy
TK Choueiri, W Xie, C Kollmannsberger… - The Journal of …, 2011 - auajournals.org
… Vascular endothelial growth factor targeted therapy is a standard of care in patients with
metastatic renal cell carcinoma. The role of cytoreductive nephrectomy in the era of novel …
metastatic renal cell carcinoma. The role of cytoreductive nephrectomy in the era of novel …
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