Vascular protection: a novel nonangiogenic cardiovascular role for vascular endothelial growth factor

I Zachary, A Mathur, S Yla-Herttuala… - … , and vascular biology, 2000 - Am Heart Assoc
… the concept that vascular protection is an important … , vascular protection is a distinct
mechanism through which VEGF can enhance antiproliferative, antithrombotic, and other protective

Insulin-like growth factor-1 as a vascular protective factor

E Conti, C Carrozza, E Capoluongo, M Volpe, F Crea… - Circulation, 2004 - Am Heart Assoc
… They reduce growth hormone (GH) release and the serum concentrations of … growth factors
(epidermal growth factor, fibroblast growth factor, platelet-derived growth factor, and vascular

Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor

I Zachary - American Journal of Physiology-Cell Physiology, 2001 - journals.physiology.org
… a role as a vascular protective factor in the adult vasculature … vascular protection may be an
important mode of action for VEGF in the adult vasculature (103,132). Vascular protection is a …

Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting

M Mesri, M Morales-Ruiz, EJ Ackermann… - The American journal of …, 2001 - Elsevier
The protective genes that mediate endothelial cell (EC) survival during angiogenesis have
not been completely characterized. Here, we show that an antisense oligonucleotide to the …

Role of Raf in vascular protection from distinct apoptotic stimuli

A Alavi, JD Hood, R Frausto, DG Stupack, DA Cheresh - Science, 2003 - science.org
growth factor (bFGF) and vascular endothelial growth factor (VEGF) differentially activate
Raf, resulting in protection … translocation and endothelial cell protection from the intrinsic …

Vascular endothelial growth factors in cardiovascular medicine

U Testa, G Pannitteri, GL Condorelli - Journal of Cardiovascular …, 2008 - journals.lww.com
… is a new emerging area for the treatment of ischemic vascular diseases. This approach is …
of specific growth factors [vascular endothelial growth factors (VEGFs) or other growth factors

Vascular endothelial growth factor: basic science and clinical progress

N Ferrara - Endocrine reviews, 2004 - academic.oup.com
factor” from human and animal tumors. Subsequently, the angiogenic effects of various factors,
including epidermal growth factorfactors, acidic and basic fibroblast growth factors (aFGF …

[HTML][HTML] Role of vascular endothelial growth factor in the regulation of angiogenesis

N Ferrara - Kidney international, 1999 - Elsevier
… Compelling evidence indicates that vascular endothelial growth factor (VEGF) is a fundamental
regulator of normal and abnormal angiogenesis. The loss of a single VEGF allele results …

Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke

TM Hansen, AJ Moss… - Current Neurovascular …, 2008 - ingentaconnect.com
Vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang1) were originally identified
as endothelial-specific ligands regulating key functions of the vasculature important in …

Role of vascular endothelial growth factor (VEGF) in endothelial cell protection against cytotoxic agents

MÁ Castilla, C Caramelo, RM Gazapo, O Martı́n… - Life sciences, 2000 - Elsevier
… In conclusion, the present study reveals a protective mechanism of endothelial cells
against injury involving autocrine VEGF production. Moreover, the occurrence of a significant …