… signaling in the Akt/GSK-3 and Wnt pathways, 2) evidence that molecules in the Akt/GSK-3
and Wnt-related pathways … alterations in these signaling pathways are functionally significant, …

… Figure 1Schematic representation of simplified canonical Wnt signaling pathways. There
are generally two pools of β-catenin in cells. One pool is associated with cadherins, whereas …

… sequence of this GSK‐3β‐interacting protein … Wnt signaling pathway; therefore, we termed
this protein rAxin (rat Axin). rAxin interacted directly with, and was phosphorylated by, GSK‐3β…

… Beta-catenin is involved in both cell–cell adhesion and in transcriptional regulation by
the Wingless/Wnt signalling pathway. Alterations of components of this pathway have been …

… role, GSK-3β can inhibit the Wnt pathway in a … GSK-3β, increases the rate of Wnt signalling
without affecting the phosphorylation levels of β-catenin. Our results demonstrate that GSK-3β …

… properties is a regulator of this pathway.20) A common comorbidity … Wnt pathway and is
also one of the strongest genetic risk variants for type 2 DM. This study implies that Wnt pathway …

… Many studies suggest that β is the isoform that is involved in several signaling pathways
like the Wnt pathway and regulate several physiological responses (protein synthesis, gene …

… of the Wnt pathway suggests that Axin somehow interferes with the Wnt pathway, although
… To further elucidate the regulation of the Wnt signalling pathway, we attempted to isolate …

… GSK-3 in the Wnt/β-catenin signaling pathway in obesityThe aim of the study was to assess
the activity of the components of the Wnt signaling pathway … signaling pathways in the WNT …

… wnt pathway is a consequence of inhibition of GSK-3b by lithium. Using a novel assay for
GSK-3b in oocytes, we show that lithium inhibits GSK-… organizer signaling pathways generate a …