… methylation of H3K4 on the interaction between ADD 3A and the H3 tail, we introduced
analogues of non‐methylated… methylated state of H3K4. Weaker binding to the H3 tail containing …

… Structure of the COMPASS-uNCP Complex To reveal the structural basis of H2Bub-dependent
H3K4 methylation … -uNCP complex and determined its structure by single-particle cryo-EM …

… approaches centered on H3K4 methylation using yeast as a … and H3K4 methylation, as well
as structures and functions of … of H2B monoubiquitination–H3K4 methylation as a regulator …

… These findings transform our understanding of the structural basis for the regulation of MLL
… mechanism that underlies the trans-histone regulation of H3K4 methylation by H2BK120ub1…

… Although both MLL and MLL2 catalyze histone H3K4 methylation, they are proposed to play
different roles in development. MLL2 functions as an important protein in spermatogenesis […

… how de novo DNA methylation is restricted in somatic cells, whether Dnmt3a and 3b alone
are capable of discriminating H3K4 methylation status, and (if so) the structural basis for that …

… H3K4), by addition of mono-, di-, or trimethyl groups in a highly regulated manner. H3K4
methylation … level of methylation state (mono-, di-, or trimethyl) varying across the coding region ( …

… We did not detect any H3K4 methylation by Set1 alone or in the presence of putative Set1-…
that Cps60 and Cps25 are required for H3K4 methylation activity by Set1. In the reconstituted …

… H3K4 methylation activity of MLL3/4 requires binding to H4 To address the trans-histone
regulation of H3K4 methylation … MLL3/4-catalyzed H3K4 methylation in vitro using recombinant …

… Our structures of all four methylation states of H3K4 do not support a role for unconventional
hydrogen bonds from the methyl groups. Instead, WDR5 uses the subtle changes in the …