Role of the tumor microenvironment in cancer hallmarks and targeted therapy
R Naser, I Fakhoury, A El-Fouani… - International …, 2023 - spandidos-publications.com
… solid tumors. These cellular and non‑cellular stromal components form the tumor
microenvironment (TME), which co‑evolves with tumor … to be among the distinctive hallmarks of …
microenvironment (TME), which co‑evolves with tumor … to be among the distinctive hallmarks of …
[HTML][HTML] Metabolic hallmarks of tumor and immune cells in the tumor microenvironment
K Renner, K Singer, GE Koehl, EK Geissler… - Frontiers in …, 2017 - frontiersin.org
… supply and generation of building blocks for tumor growth but also contribute to … tumor
microenvironment is often based on the mutual metabolic requirements of immune cells and tumor …
microenvironment is often based on the mutual metabolic requirements of immune cells and tumor …
The tumor microenvironment shapes hallmarks of mature B-cell malignancies
KH Shain, WS Dalton, J Tao - Oncogene, 2015 - nature.com
… loss of heterozygosity of tumor-suppressor genes. However, it is critical to recognize that
even in the setting of a genetic disease, the B-cell/plasma cell tumor microenvironment (TME) …
even in the setting of a genetic disease, the B-cell/plasma cell tumor microenvironment (TME) …
Improving cancer therapies by targeting the physical and chemical hallmarks of the tumor microenvironment
Tumors are highly heterogeneous at the patient, tissue, cellular, and molecular levels. This
multi-scale heterogeneity poses significant challenges for effective therapies, which ideally …
multi-scale heterogeneity poses significant challenges for effective therapies, which ideally …
Hallmarks of cancer: new dimensions
D Hanahan - Cancer discovery, 2022 - AACR
… We further recognized that the tumor microenvironment (TME), herein defined to be composed
of heterogeneous and interactive populations of cancer cells and cancer stem cells along …
of heterogeneous and interactive populations of cancer cells and cancer stem cells along …
Tumor microenvironment indoctrination: an emerging hallmark of cancer
JG Goetz - Cell adhesion & migration, 2012 - Taylor & Francis
… that the corrupted tumor microenvironment becomes a full … tumor angiogenesis and
extracellular matrix remodeling. Nevertheless, the recent emergence of the tumor microenvironment …
extracellular matrix remodeling. Nevertheless, the recent emergence of the tumor microenvironment …
Key promoters of tumor hallmarks
K Mortezaee, J Majidpoor - International journal of clinical oncology, 2022 - Springer
… Evolution of tumor hallmarks is a result of accommodation of tumor cells with their nearby
milieu called tumor microenvironment (TME). Accommodation or adaptive responses is highly …
milieu called tumor microenvironment (TME). Accommodation or adaptive responses is highly …
Hallmarks of cancer: interactions with the tumor stroma
… The stromal elements of tumors hold prognostic, … tumor microenvironment are continually
identified. Herein we review the current understanding of tumor cell interactions with the tumor …
identified. Herein we review the current understanding of tumor cell interactions with the tumor …
[HTML][HTML] Protein glycosylation and tumor microenvironment alterations driving cancer hallmarks
… reflection in the glycoproteome is driven by microenvironmental cues and these events act
… hallmarks, with emphasis on the crosstalk between glycans and the tumor microenvironment …
… hallmarks, with emphasis on the crosstalk between glycans and the tumor microenvironment …
[HTML][HTML] Imaging hallmarks of the tumor microenvironment in glioblastoma progression
… measures of tumor progression are only tumor size, we … tumor microenvironment that
were not solely related to the size of the tumor and changes might develop earlier during tumor …
were not solely related to the size of the tumor and changes might develop earlier during tumor …
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