Handling of missing data in long‐term clinical trials: a case study
M Janssens, G Molenberghs… - Pharmaceutical …, 2012 - Wiley Online Library
… Missing data in clinical trials is a well-known problem, and … study shows how well-established
missing data theory can be applied to efficacy data collected in a long-term open-label trial …
missing data theory can be applied to efficacy data collected in a long-term open-label trial …
[图书][B] Preventing and treating missing data in longitudinal clinical trials: a practical guide
CH Mallinckrodt - 2013 - books.google.com
… missing data in longitudinal clinical trials. Based on his extensive experience with missing
data… and on ways to prevent missing data through appropriate trial design and conduct. He …
data… and on ways to prevent missing data through appropriate trial design and conduct. He …
'Intention-to-treat'meets 'missing data': implications of alternate strategies for analyzing clinical trials data
C Nich, KM Carroll - Drug and alcohol dependence, 2002 - Elsevier
… Problems associated with missing data … that missing data place on how data from a clinical
trial may be analyzed. For example, in a longitudinal study where multiple data points are …
trial may be analyzed. For example, in a longitudinal study where multiple data points are …
Imputation methods for missing outcome data in meta-analysis of clinical trials
… trials reveals the overall conclusion to be robust to different assumptions about the missing
data. … Wood AM, White IR, Thompson SG Are missing outcome data adequately handled? A …
data. … Wood AM, White IR, Thompson SG Are missing outcome data adequately handled? A …
Methods for missing data handling in randomized clinical trials with nonnormal endpoints with application to a phase III clinical trial
C Fan, D Zhang, L Wei, G Koch - … in Biopharmaceutical Research, 2016 - Taylor & Francis
… incomplete datasets. Over the past several decades, statistical methods to handle missing
data under certain presumed missing … in solving problems where missing data are present. We …
data under certain presumed missing … in solving problems where missing data are present. We …
Missing data in randomised controlled trials: a practical guide
JR Carpenter, MG Kenward - 2007 - researchonline.lshtm.ac.uk
… This monograph reviews the issues of raised by missing data in clinical trials, and describes
… by missing data. We propose a systematic approach to handling missing data in clinical trials…
… by missing data. We propose a systematic approach to handling missing data in clinical trials…
Intricacy of missing data in clinical trials: Deterrence and management
… Properly conducted clinical trial can limit the extent of missing data. This article aims … study
design and its conduct which leads to missing values. Some measures for improving the study …
design and its conduct which leads to missing values. Some measures for improving the study …
How can I deal with missing data in my study?
DA Bennett - Australian and New Zealand journal of public health, 2001 - Elsevier
… The missing data methods described in this article deal with incomplete data from the perspective
of … of longitudinal data analysis methods for clinical trials and epidemiological studies. …
of … of longitudinal data analysis methods for clinical trials and epidemiological studies. …
[图书][B] Missing data in clinical studies
G Molenberghs, M Kenward - 2007 - books.google.com
… In Chapter 26 we analyse quality-of-life data from a clinical trial with breast cancer patients.
We must emphasize that, in keeping with the theme of the book, our coverage should not in …
We must emphasize that, in keeping with the theme of the book, our coverage should not in …
A systematic review of randomised controlled trials in rheumatoid arthritis: the reporting and handling of missing data in composite outcomes
… set of disease activity measures for rheumatoid arthritis clinical trials. The Committee on
Outcome Measures in Rheumatoid Arthritis Clinical Trials. Arthritis Rheum. 1993;36(6):729–40. …
Outcome Measures in Rheumatoid Arthritis Clinical Trials. Arthritis Rheum. 1993;36(6):729–40. …