Are missing data adequately handled in cluster randomised trials? A systematic review and guidelines

K Díaz-Ordaz, MG Kenward, A Cohen… - Clinical …, 2014 - journals.sagepub.com
… , in particular, establishing the prevalence of missing data and describing the current handling
… guidelines for handling missing values in the analysis of cluster randomised trials, and for …

Missing data in clinical trials for weight management

BW McEvoy - Journal of Biopharmaceutical Statistics, 2016 - Taylor & Francis
… also used in the FDA analyses to address missing data. The goal of this article is to illustrate
challenges and considerations associated with the handling of missing data in clinical trials. …

Missing data in alcohol clinical trials: a comparison of methods

KA Hallgren, K Witkiewitz - … and Experimental Research, 2013 - Wiley Online Library
… The goal of the current study was to examine various missing data assumptions and … This
study examined the effect of 5 methods for handling missing data under a variety of conditions …

Handling missing data in vaccine clinical trials for immunogenicity and safety evaluation

X Li, WWB Wang, GF Liu, ISF Chan - Journal of Biopharmaceutical …, 2011 - Taylor & Francis
… Finally, we would like to reiterate that the best way to handle missing data is to … missing
data in a study, the less the extent of missing data, the more robust and convincing the study

[HTML][HTML] A four-step strategy for handling missing outcome data in randomised trials affected by a pandemic

S Cro, TP Morris, BC Kahan, VR Cornelius… - BMC medical research …, 2020 - Springer
… We consider handling missing data arising due to (i) participant infection, (ii) treatment
disruptions and (iii) loss to follow-up. We consider both settings where treatment effects for a ‘…

Methods for missing data handling in phase III clinical trials with nonnormal endpoints and nonnormal covariates

C Fan, L Wei, GG Koch - Statistics in Biopharmaceutical Research, 2019 - Taylor & Francis
… (Citation2016), we apply the missing data handling methods investigated in the current …
data from a subgroup of this study. In the selected subgroup of this Phase III clinical trial, there …

Handling missing data

TD Pigott - The handbook of research synthesis and meta …, 2009 - books.google.com
… , researchers will find that studies in a research synthesis … missing data that occur in a
research synthesis, and discuss strategies synthesists can use when faced with missing data

[PDF][PDF] A review of methods for handling missing data in the form of dropouts in longitudinal clinical trials

A Satty, H Mwambi - Bull Pharm Med Sci (BOPAMS), 2014 - bopams.kypublications.com
… We discuss the ML as a method for handling missing data. Examples for applying ML to
missing data problems can be found in Little and Rubin (2002). Furthermore, in a variety of …

Advanced Statistics: Missing Data in Clinical Research—Part 1: An Introduction and Conceptual Framework

JS Haukoos, CD Newgard - Academic Emergency Medicine, 2007 - Wiley Online Library
… of missing data in clinical research and their relationships to specific methods of handling
missing data, and 2) to describe several simple, yet naive, methods for handling missing data

[HTML][HTML] Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods

MA Elobeid, MA Padilla, T McVie, O Thomas… - PloS one, 2009 - journals.plos.org
… These results suggest that, at least when missingness is unrelated to treatment assignment,
all of the approaches we evaluated for handling missing data are adequate for protecting the …