Handling Missing Data in Oncology Clinical Trials

XN Li, C Chen, XF Fan - Oncology Clinical Trials: Successful …, 2018 - books.google.com
HANDLING MISSING DATA IN STATISTICAL … of missing data, statistical analyses often
involve missing data imputation. In order to maintain the objectivity of the missing data handling

Reporting and dealing with missing quality of life data in RCTs: has the picture changed in the last decade?

S Fielding, A Ogbuagu, S Sivasubramaniam… - … of Life Research, 2016 - Springer
… to different missing data assumptions. Medical journals can help to improve the situation by
requiring higher standards of reporting and analytical methods to deal with missing data, and …

Missing data in longitudinal clinical trials part A: Design and conceptual issues

PW Lavori, CH Brown, N Duan, RD Gibbons… - Psychiatric …, 2008 - journals.healio.com
… that serious missing data problems result from a trial design … ciency by using intentionally
incomplete data. It also discusses … , rather than resolve missing data issues. Intentionality is a …

Multiple imputation: dealing with missing data

MCM de Goeij, M Van Diepen, KJ Jager… - Nephrology Dialysis …, 2013 - academic.oup.com
… Furthermore, it is likely that, in clinical research, the two types of missing data are mixed
and it is very difficult to assess which type is (most) present. When using the method of LOCF, …

Handling missing data in self‐report measures

SM Fox‐Wasylyshyn… - Research in nursing & …, 2005 - Wiley Online Library
… validity of research results may be dependent on investigators’ approach to handling missing
data, … Using multiple imputation for analysis of incomplete data in clinical research. Nursing …

Treatment of missing data in follow-up studies of randomised controlled trials: a systematic review of the literature

TR Sullivan, LN Yelland, KJ Lee, P Ryan… - Clinical …, 2017 - journals.sagepub.com
… used to handle missing data depends on the mechanism responsible for the data being
missing. … cohorts (as this would lead to additional complexities in handling missing data). Where …

Missing repeated measures data in clinical trials

SL Pugh, PD Brown, D Enserro - Neuro-Oncology Practice, 2022 - academic.oup.com
missing data in a clinical trial as much as possible (Figure 1). Efforts to decrease missing data
must begin with the design of the trial… or repeated measures data should be clearly defined …

The treatment of missing data in a large cardiovascular clinical outcomes study

RJ Little, J Wang, X Sun, H Tian, EY Suh… - Clinical …, 2016 - journals.sagepub.com
Research Council study provides recommendations for limiting missing data in clinical trial
design … robustness of findings to alternative assumptions about the missing data. A Food and …

The reporting and handling of missing data in longitudinal studies of older adults is suboptimal: a methodological survey of geriatric journals

C Okpara, C Edokwe, G Ioannidis… - BMC medical research …, 2022 - Springer
missing data. Complete case analysis was the most common method for handling missing
data … individual observations due to missing data, at the initial phase of study inclusion or at …

Missing radiographic data handling in randomized clinical trials in rheumatoid arthritis

X Huang, L Jiao, L Wei, H Quan, L Teoh… - Journal of …, 2013 - Taylor & Francis
… of missing values due to dropout or unreadable images. There are no uniform ways to handle
missing radiographic data, … We also evaluate four other missing data imputation methods …