… HDL-C at the normal level is associated with good HDL quality and functionality. Nevertheless,
high HDL quantity is not always accompanied by good HDL … advances in HDL quantity, …

… -centric signaling properties of HDL 2 versus HDL 3 need to be explored. … HDL biology
and therapeutics, 22 these results further echo the concept that HDL quality rather than quantity …

… It should be considered that the main HDL … We propose HDL as bidirectional lipid vectors
carrying lipids from and to tissues according to their local context. Lipid influx mediated by HDL …

… This paradigm shift to a qualitative rather than quantitative assessment of HDL might explain
the failure of several HDL raising therapies to demonstrate a reduction in cardiovascular …

… of HDL in CVD risk assessment, emphasizing the need to focus on HDL quantity and HDL
… that suggest HDL particle number and size rather than HDL quantity only is warranted [13]. …

… role of HDL; quantity (circulating plasma levels of HDL-C) and HDL quality (… of HDL
components). Plasma concentrations of HDL-C (which indicate cholesterol content within all α-HDL …

… , and this also accounts for HDL-C levels which are only … Despite this overwhelming
quantity of data, some laboratories … This report will lead to a paradigm shift in clinical lipidology …

… Blood glucose response is determined by the quality as well as the quantity of … GI or GL
values have an inverse association with HDL levels and a positive association with triglycerides. …

… for HDL subfractions and propose a paradigm to define the dynamic process of HDL
metabolism with multiple static laboratory measurements. We acknowledge that the various HDL …

… Recent evidence suggests that the quality of HDL particles (which depends on shape, size
… HDL functionality) may be more important than their quantity. The functionality of HDL is …