Cetuximab-containing combinations in locally advanced and recurrent or metastatic head and neck squamous cell carcinoma

M Taberna, M Oliva, R Mesía - Frontiers in oncology, 2019 - frontiersin.org
… , cetuximab-mediated immunogenicity through antibody dependent cell cytotoxicity (ADCC)
has encouraged the evaluation of combined … on the role of cetuximab in HNSCC in the past …

Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab

D Curran, J Giralt, PM Harari, KK Ang… - Journal of clinical …, 2007 - ascopubs.org
… impact on QoL of cetuximab combined with radiotherapy is … plus cetuximab was well
tolerated and cetuximab did not … the full dose of cetuximab in combination with radiotherapy. …

[HTML][HTML] … of the combination of cetuximab and weekly paclitaxel in the first-line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of head …

R Hitt, A Irigoyen, H Cortes-Funes, JJ Grau… - Annals of …, 2012 - Elsevier
… the combination of cetuximab with platinum/5-FU. Evidence indicates that the combination of
cetuximab has greater antitumor activity than cetuximab alone [24, 25], suggesting that this …

Cetuximab in metastatic or recurrent head and neck cancer: the EXTREME trial

F Rivera, A García-Castaño, N Vega… - Expert review of …, 2009 - Taylor & Francis
… In this study, combined treatment of radiotherapy and cetuximab did not result in higher
toxicity, but significantly increased both locoregional control (LRC; 2-year LRC rate: 50 vs 41%; …

… of taxanes in combination with cetuximab for the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: evidence, advantages, and …

J Guigay, M Tahara, L Licitra, U Keilholz… - Frontiers in …, 2019 - frontiersin.org
… by cetuximab maintenance treatment, significantly improved patient outcomes compared
with chemotherapy alone (5). This combination … studies, for combining cetuximab and taxane-…

Cetuximab: a review of its use in squamous cell carcinoma of the head and neck and metastatic colorectal cancer

SKA Blick, LJ Scott - Drugs, 2007 - Springer
… Phase I study of antiepidermal growth factor receptor antibody cetuximab in combination with
radiation therapy in patients with advanced head and neck cancer. J Clin Oncol 2001 Jul 1; …

Radiotherapy combined with cetuximab for locally advanced head and neck cancer: results and toxicity

CM Acevedo-Henao, G Valette, P Miglierini, E Lefur… - Cancer …, 2012 - Elsevier
… of the combined treatment with radiotherapy and cetuximab for locally advanced head and
neck … cell head and neck carcinoma were treated with radiotherapy (70Gy/35 fractions) and …

Phase I study of anti–epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer

F Robert, MP Ezekiel, SA Spencer… - Journal of clinical …, 2001 - ascopubs.org
… identified cetuximab as a radiosensitizer, a phase I study was undertaken to assess the
interaction of cetuximab … The purposes of this study were to establish a safety profile of cetuximab

… II study of cetuximab in combination with cisplatin or carboplatin and fluorouracil in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

J Bourhis, F Rivera, R Mesia, A Awada… - Journal of clinical …, 2006 - ascopubs.org
… triple combination regimen (cetuximab/cisplatin [carboplatin]/FU) may provide a useful
therapeutic approach. A randomized trial investigating this triple combination is now warranted. …

… motolimod to standard combination chemotherapy and cetuximab treatment of patients with squamous cell carcinoma of the head and neck: the active8 randomized …

RL Ferris, NF Saba, BJ Gitlitz, R Haddad… - JAMA …, 2018 - jamanetwork.com
… , fluorouracil, and cetuximab combination treatment is the standard of care for first-line
recurrent and/or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) (…