High serum levels of YKL‐40 in patients with squamous cell carcinoma of the head and neck are associated with short survival
A Roslind, JS Johansen, IJ Christensen… - … journal of cancer, 2008 - Wiley Online Library
… showed YKL-40 expression in the malignant tumor cells. In conclusion, serum YKL-40 was
… referred to as squamous cell carcinomas of the head and neck (HNSCC), are common types …
… referred to as squamous cell carcinomas of the head and neck (HNSCC), are common types …
Association of serum level of YKL-40 in patients with squamous cell carcinoma of the head and neck with survival
A Roslind, JS Johansen, IJ Christensen… - Journal of Clinical …, 2006 - ascopubs.org
… Patients with stage 1 disease had lower, but non-significant, serum YKL-40 compared to …
serum YKL-40 had significantly shorter survival than patients with normal serum YKL-40 (33 …
serum YKL-40 had significantly shorter survival than patients with normal serum YKL-40 (33 …
Is YKL-40 a new therapeutic target in cancer?
JS Johansen, BV Jensen, A Roslind… - Expert opinion on …, 2007 - Taylor & Francis
… A total of 13 studies have demonstrated that elevated serum YKL-40 in patients with breast,
colorectal, head and neck, renal cell, prostate, ovarian and small cell lung cancer, malignant …
colorectal, head and neck, renal cell, prostate, ovarian and small cell lung cancer, malignant …
YKL-40—a protein in the field of translational medicine: a role as a biomarker in cancer patients?
NA Schultz, JS Johansen - Cancers, 2010 - mdpi.com
… elevated plasma YKL-40 is defined as an age-corrected plasma YKL-40 concentration
higher than the 95 th or the 97 th percentile of plasma YKL-40 in healthy age-matched subjects. …
higher than the 95 th or the 97 th percentile of plasma YKL-40 in healthy age-matched subjects. …
Chitinase-3-like protein 1 (YKL-40) expression in squamous cell skin cancer
J Salomon, A Piotrowska, Ł Matusiak… - Anticancer …, 2018 - ar.iiarjournals.org
… YKL-40 plays a role in proliferation and differentiation of malignant cells. The aim of this study
was to examine whether YKL-40 … The tissue expression of YKL-40 was assessed using an …
was to examine whether YKL-40 … The tissue expression of YKL-40 was assessed using an …
Prognostic value of YKL-40 in solid tumors: A meta-analysis of 41 cohort studies
B Bian, L Li, J Yang, Y Liu, G Xie, Y Zheng… - Cancer cell …, 2019 - Springer
… YKL-40 was significantly associated with poor OS (HR, 1.44; 95% CI 1.33–1.56). We also
found that elevated serum/plasma YKL-40 … effect of serum/plasma YKL-40 was not statistically …
found that elevated serum/plasma YKL-40 … effect of serum/plasma YKL-40 was not statistically …
Elevated pretreatment serum concentration of YKL‐40—An independent prognostic biomarker for poor survival in patients with metastatic nonsmall cell lung cancer
I Thöm, B Andritzky, G Schuch, I Burkholder, L Edler… - Cancer, 2010 - Wiley Online Library
… YKL-40 levels have been associated with a poor prognosis.15, 22, 25-36 Serum YKL-40 was
a … who had lower serum YKL-40 levels and suggested the use of YKL-40 as a biomarker for …
a … who had lower serum YKL-40 levels and suggested the use of YKL-40 as a biomarker for …
Prognostic and predictive role of YKL-40 in anal squamous cell carcinoma: a serological and tissue-based analysis in a multicentric cohort
A Gambella, R Senetta, EC Falco, AA Ricci… - Frontiers in …, 2024 - frontiersin.org
… These findings are novel in the ASC setting but in line with data reported in head and neck
and … In particular, high serum YKL-40 identifies a subgroup of patients with head and neck …
and … In particular, high serum YKL-40 identifies a subgroup of patients with head and neck …
Extraneural metastases in glioblastoma patients: two cases with YKL-40-positive glioblastomas and a meta-analysis of the literature
A Elena, C Melina, N Raffaele, B Carlo, N Vittoria… - Neurosurgical …, 2016 - Springer
… YKL-40 was positive in both our cases, both in parental and … YKL-40 expression associated
with the lack of EGFR … However, we describe two metastasizing GBM that labeled for YKL-40, …
with the lack of EGFR … However, we describe two metastasizing GBM that labeled for YKL-40, …
YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: Implications for its use in tumor models
LC Böckelmann, T Felix, S Calabrò, U Schumacher - Cellular Oncology, 2021 - Springer
… demonstrated elevated YKL-40 serum levels in cancer patients and found YKL-40 to be
correlated with a poor prognosis and disease severity in some tumor entities. YKL-40 was …
correlated with a poor prognosis and disease severity in some tumor entities. YKL-40 was …
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