Targeting hypoxia to overcome radiation resistance in head & neck cancers: real challenge or clinical fairytale?

R Baumann, R Depping, M Delaperriere… - Expert review of …, 2016 - Taylor & Francis
… clinical challenge Head and neck cancers account for about 5% of all cancers worldwide. …
) being the backbone for small and operable tumors. However, a significant subset of patients …

Global epidemiology of head and neck cancers: a continuing challenge

B Gupta, NW Johnson, N Kumar - Oncology, 2016 - karger.com
Background: Head and neck cancers (HNCs) continue to remain a significant public health
burden worldwide, causing significant mortality and morbidity despite significant clinical …

Immunotherapy in head and neck cancer: The great challenge of patient selection

M Napolitano, FM Schipilliti, L Trudu… - Critical reviews in oncology …, 2019 - Elsevier
… the therapeutic landscape in head and neck cancer. However, … As far as the head and neck
cancer is concerned, all pivotal … At present no data from the real life is available in this setting…

Immunotherapy in head and neck cancers: a new challenge for immunologists, pathologists and clinicians

S Outh-Gauer, M Alt, C Le Tourneau, J Augustin… - Cancer Treatment …, 2018 - Elsevier
… Various tumor antigens (Ly6K, CDCA1, IMP3…) that have been identified in non-HPV head
and neck cancer have been shown to elicit TL response in humans [95]. Patients showing a …

[HTML][HTML] Oligometastatic head and neck cancer: challenges and perspectives

H Bahig, SH Huang, B O'Sullivan - Cancers, 2022 - mdpi.com
… oligometastasis in head and neck cancer. We also describe the challenges and opportunities
in … free of disease 4–5 years after, raising the real possibility of cure in some patients [58]. …

Liquid biopsy in head and neck cancer: promises and challenges

T Nonaka, DTW Wong - Journal of dental research, 2018 - journals.sagepub.com
… Liquid biopsy has been increasingly considered as an option for molecular characterization
and detection of cancer as it can provide real-time information about cancer in a minimally …

Adaptive radiation therapy in head and neck cancer for clinical practice: state of the art and practical challenges

O Veresezan, I Troussier, A Lacout, S Kreps… - Japanese journal of …, 2017 - Springer
… Due to alteration of patient anatomy, changes in tissue density/volumes and tumor shrinkage
over the course of treatment, treatment accuracy may be challenged. This may result in …

[HTML][HTML] Challenges in combining immunotherapy with radiotherapy in recurrent/metastatic head and neck cancer

G Plavc, T Jesenko, M Oražem, P Strojan - Cancers, 2020 - mdpi.com
… of immunoradiotherapy in head and neck cancer are discussed. The … tumors. However, the
trials using immunoradiotherapy in patients with recurrent or metastatic head and neck cancer

Epidemiology of head and neck cancer: magnitude of the problem

L Döbróssy - Cancer and Metastasis Reviews, 2005 - Springer
head and neck cancers is cause for great concern, particularly in Central-Eastern Europe.
The great majority of these cancers … lesions and early invasive cancers; however, no study as …

[PDF][PDF] MR-guided radiotherapy for head and neck cancer: current developments, perspectives, and challenges

S Boeke, D Mönnich, JE Van Timmeren… - Frontiers in …, 2021 - frontiersin.org
… Figure 2 depicts a real-life patient positioning for HNC … Challenging fields of research could
be not only the decrease of … the specific and challenging indication of head and neck cancer. …