Mechanisms of endothelial cell heterogeneity in health and disease
WC Aird - Circulation research, 2006 - Am Heart Assoc
… endothelium in postcapillary venules regulates leukocyte trafficking; capillary endothelial
cells … , discontinuous endothelium in hepatic sinusoids); and endothelial cells from different …
cells … , discontinuous endothelium in hepatic sinusoids); and endothelial cells from different …
Organ/tissue-specific vascular endothelial cell heterogeneity in health and disease
T Minami, M Muramatsu, T Kume - Biological and Pharmaceutical …, 2019 - jstage.jst.go.jp
… differentiated endothelial cells, in which heterogeneity has long … of vascular-bed heterogeneity
and characterization, this … -governed endothelial cell phenotypic changes. These involve …
and characterization, this … -governed endothelial cell phenotypic changes. These involve …
New technologies with increased precision improve understanding of endothelial cell heterogeneity in cardiovascular health and disease
… Endothelial cell heterogeneity revealed by cell-specific sequencing. Endothelial cells (ECs)
exhibit phenotypic differences that stem from inherent organo-specific, vessel-specific, and …
exhibit phenotypic differences that stem from inherent organo-specific, vessel-specific, and …
Deciphering endothelial heterogeneity in health and disease at single-cell resolution: progress and perspectives
LM Becker, SH Chen, J Rodor… - Cardiovascular …, 2023 - academic.oup.com
… Endothelial cells (ECs) constitute the inner lining of vascular … diseases, thereby representing
realistic therapeutic targets. However, it has become evident that ECs are heterogeneous, …
realistic therapeutic targets. However, it has become evident that ECs are heterogeneous, …
Heterogeneity of vascular endothelial cells in normal and disease states
E Thorin, SM Shreeve - Pharmacology & therapeutics, 1998 - Elsevier
… endothelium (see references above), none have focused on endothelial cell heterogeneity.
… what is known about heterogeneity among the endothelium within species. Furthermore, we …
… what is known about heterogeneity among the endothelium within species. Furthermore, we …
Endothelial cell heterogeneity and plasticity in health and disease—new insights from single-cell studies
LM Becker, A Pasut, A Cuypers, P Carmeliet - The Vasculome, 2022 - Elsevier
… single-cell RNA sequencing (scRNAseq) studies, here we highlight two main examples of EC
plasticity and heterogeneity: (… in health and disease with a focus on metabolic plasticity and …
plasticity and heterogeneity: (… in health and disease with a focus on metabolic plasticity and …
[图书][B] Endothelial cells in health and disease
WC Aird - 2005 - books.google.com
… that phenotypic heterogeneity is mediated, in … of endothelial cell biology-namely, in vitro
cell culture has fallen short in providing insight into the spatial and temporal dynamics of this cell …
cell culture has fallen short in providing insight into the spatial and temporal dynamics of this cell …
Endothelial cell heterogeneity
WC Aird - Cold Spring Harbor perspectives in …, 2012 - perspectivesinmedicine.cshlp.org
… heterogeneity of endothelial cells during angiogenesis. For example, endothelial sprouts
comprise leading-edge tip cells followed by morphologically and functionally distinct stalk cells. …
comprise leading-edge tip cells followed by morphologically and functionally distinct stalk cells. …
Exploring the role of endothelial cell resilience in cardiovascular health and disease
Y Gao, ZS Galis - Arteriosclerosis, thrombosis, and vascular biology, 2021 - Am Heart Assoc
… health. In this brief review, we applied this working definition of resilience to the endothelium
and its constitutive parts, the endothelial cells (… The contribution of endothelial heterogeneity …
and its constitutive parts, the endothelial cells (… The contribution of endothelial heterogeneity …
Vascular endothelial cell specification in health and disease
C Marziano, G Genet, KK Hirschi - Angiogenesis, 2021 - Springer
… Blood endothelial cell development … Each vessel type is lined with ECs that not only exhibit
a high degree of heterogeneity among different sections of the vascular tree, but also exhibit …
a high degree of heterogeneity among different sections of the vascular tree, but also exhibit …
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