… The kynurenine pathway (KP) of L-tryptophan metabolism is increasingly recognised as
a critical source of neuroactive metabolites with relevance for health and disease. There is …

… the kynurenine pathway. The biological activity of kynurenine and its metabolites (kynurenines)
is … of therapeutic strategies which aim to interfere with the kynurenine pathway. However, …

… imbalances in tryptophan and kynurenines have been found. … kynurenine pathway might
be contributing to disease development, and the concentrations of tryptophan and kynurenines …

… related to inflammation and the kynurenine pathway, including neopterin, kynurenine:tryptophan
ratio, C-reactive protein, tryptophan, and 6 kynurenines, as potential predictors of all-…

… The major route of Trp degradation, the kynurenine pathway (KP), produces a range of
biologically active metabolites that can impact or be impacted by a variety of body systems, …

… The kynurenine pathway is … kynurenine metabolites can participate in numerous
neurodegenerative disorders (Alzheimer disease, amyotrophic lateral sclerosis, Huntington disease…

… The kynurenine pathway (KP) of tryptophan metabolism has emerged in recent years as a
key … two major pathways, the kynurenine pathway (KP) and the methoxyindole pathway. The …

… of the kynurenine pathway has … brain diseases, was viewed almost exclusively through the
lens of the well-established metabolite serotonin. With increasing recognition that kynurenine …

… the rate-limiting step in the kynurenine pathway of tryptophan degradation, is strongly induced
by … This review provides an overview of the emerging field of the kynurenine pathway of …

… inflammatory disease. However, many of its metabolites, collectively termed “kynurenines”, …
of the impact of the kynurenines on several physiological pathways and symptom domains. In …