… A challenging concern for understanding complex metabolic diseases such as type 2 …
between metabolic pathways and disease phenotypes. Nonetheless, foundational metabolic …

… , and bile acid metabolites/pathways show strong preclinical evidence for involvement in …
of disease-related alterations in microbial metabolic pathways in Alzheimer’s Disease, …

Peroxisomes play a key role in human physiology as exemplified by the devastating
consequences of a defect in peroxisome biogenesis as observed in patients affected by Zellweger …

… We have described in this study how key features of metabolic signaling pathways can
modulate age-related disease risk and longevity. Novel approaches and unexpected discoveries …

… metabolic pathways. Maintenance of tissue and cellular homeostasis by functional fine-tuning
of essential metabolic pathways is … in glucose and lipid metabolism, food intake regulation, …

… regulators sense hormonal and metabolic cues and manage … metabolic pathways and the
organ systems. The alteration of this cross talk contributes to the pathophysiology of metabolic, …

… metabolic pathways. Furthermore, knowledge of key biochemical reactions in the two dozen
or so core metabolic pathways in … , and the many genetic diseases that are caused by the …

… metabolic homeostasis in the context of health and disease. We also highlight the potential
of targeting immuno-metabolic pathways … strategy to treat obesity and associated diseases. …

… The modeling of metabolic pathways has been applied to better understand disease-state …
Metabolic pathway engineering has been used to generate cells with novel biochemical …

… pathways influencing sulfur metabolism and their recognized and potential contributions to
colonic health and disease. … Various microbial metabolic pathways influence the composition …