Arginine metabolism and nutrition in growth, health and disease
… dietary levels of arginine are high, intestinal synthesis of citrulline from glutamine and
glutamate may be inhibited for sparing of glutamine and glutamate for other metabolic pathways. …
glutamate may be inhibited for sparing of glutamine and glutamate for other metabolic pathways. …
Myocardial fatty acid metabolism in health and disease
… The regulation of fatty acid β-oxidation occurs at almost every step of the metabolic pathway,
including at the level of lipoprotein lipase (LPL), fatty acid uptake into the cardiac myocyte, …
including at the level of lipoprotein lipase (LPL), fatty acid uptake into the cardiac myocyte, …
Regulation of metabolic health and aging by nutrient-sensitive signaling pathways
NE Cummings, DW Lamming - Molecular and cellular endocrinology, 2017 - Elsevier
… In this review, we discuss the effects of a CR diet on metabolism and healthspan, and …
quality may influence metabolic health. Finally, we discuss key metabolic pathways which may …
quality may influence metabolic health. Finally, we discuss key metabolic pathways which may …
Unlocking human brain metabolism by genome-scale and multiomics metabolic models: relevance for neurology research, health, and disease
… of multiomics modeling for metabolic diseases and computational … of Alzheimer's disease,
Parkinson's disease, migraine, stroke, … of the metabolic pathways into three categories: …
Parkinson's disease, migraine, stroke, … of the metabolic pathways into three categories: …
[PDF][PDF] … METABOLISM, HEALTH AND DISEASE-A REVIEW. PART 2: FATTY ACID PHYSIOLOGICAL ROLES AND APPLICATIONS IN HUMAN HEALTH AND DISEASE …
LS Kremmyda, E Tvrzicka… - Biomedical Papers of …, 2011 - biomed.papers.upol.cz
… FA are also ligands of nuclear receptors which take part in the subcellular control of metabolic
pathways. Covalent modification of proteins by FA acylation enables their incorporation …
pathways. Covalent modification of proteins by FA acylation enables their incorporation …
The SLC22 transporter family: a paradigm for the impact of drug transporters on metabolic pathways, signaling, and disease
SK Nigam - Annual review of pharmacology and toxicology, 2018 - annualreviews.org
… Nevertheless, analyses of knockout mice and other data indicate that SLC22 transporters
regulate key metabolic pathways and levels of signaling molecules (eg, gut microbiome …
regulate key metabolic pathways and levels of signaling molecules (eg, gut microbiome …
De novo lipogenesis in health and disease
F Ameer, L Scandiuzzi, S Hasnain, H Kalbacher… - Metabolism, 2014 - Elsevier
… ) is a complex and highly regulated metabolic pathway. In normal … In human body this pathway
is primarily active in liver and … Deregulations in the lipogenic pathway are associated with …
is primarily active in liver and … Deregulations in the lipogenic pathway are associated with …
Paediatric obesity: a systematic review and pathway mapping of metabolic alterations underlying early disease processes
M De Spiegeleer, E De Paepe, L Van Meulebroek… - Molecular …, 2021 - Springer
… This systematic review revealed that the main metabolites at the crossroad of dysregulated
metabolic pathways underlying childhood obesity could be tracked down to one central …
metabolic pathways underlying childhood obesity could be tracked down to one central …
Bile acids in glucose metabolism in health and disease
H Shapiro, AA Kolodziejczyk, D Halstuch… - Journal of Experimental …, 2018 - rupress.org
… BAs are derived from catabolism of cholesterol in hepatocytes in a process that involves
two principal pathways and activation of at least 17 hepatic enzymes. The classical pathway, …
two principal pathways and activation of at least 17 hepatic enzymes. The classical pathway, …
Metabolic basis of creatine in health and disease: a bioinformatics-assisted review
… ], the ATP-dependent thermogenic pathways may play a key role in diet-induced thermogenesis
[125]. Nowadays, it is hypothesized that Cr metabolism may also provide an alternative …
[125]. Nowadays, it is hypothesized that Cr metabolism may also provide an alternative …