p38 MAPK pathway in the heart: new insights in health and disease
R Romero-Becerra, AM Santamans… - International Journal of …, 2020 - mdpi.com
The p38 mitogen-activated kinase (MAPK) family controls cell adaptation to stress stimuli. p38
… In this review, we summarize the current understanding of the role of the p38 pathway in …
… In this review, we summarize the current understanding of the role of the p38 pathway in …
[HTML][HTML] p38 MAP-kinases pathway regulation, function and role in human diseases
A Cuenda, S Rousseau - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
… The MKKK responsible for activating the p38 MAPK pathways appears to be cell type and …
of JNK pathway. In contrast, JIP4 appears to be a new component of the p38 MAPK pathway …
of JNK pathway. In contrast, JIP4 appears to be a new component of the p38 MAPK pathway …
Diversity and versatility of p38 kinase signalling in health and disease
B Canovas, AR Nebreda - Nature reviews Molecular cell biology, 2021 - nature.com
… Given all of the processes that p38 kinases can potentially control, dysregulation of this
pathway has been linked to several diseases, suggesting that pharmacological targeting of p38 …
pathway has been linked to several diseases, suggesting that pharmacological targeting of p38 …
MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets
AJ Muslin - Clinical science, 2008 - portlandpress.com
… research attempting to link these signalling pathways to cardiovascular disease. In the
present review, the role of the ERK, JNK and p38 MAPK cascades in the pathophysiology of …
present review, the role of the ERK, JNK and p38 MAPK cascades in the pathophysiology of …
MAP kinase pathways activated by stress: the p38 MAPK pathway
T Obata, GE Brown, MB Yaffe - Critical care medicine, 2000 - journals.lww.com
… Furthermore, fibrillar β-amyloid, the major component of senile plaques in Alzheimer's
disease, can activate p38 MAPK in primary rat microglia and in human THP1 monocytes (163) . …
disease, can activate p38 MAPK in primary rat microglia and in human THP1 monocytes (163) . …
p38 signalling pathway
JJ Sanz-Ezquerro, A Cuenda - International Journal of Molecular …, 2021 - mdpi.com
… members of the p38MAPK pathways have joined the group of signalling pathways involved
in the development of neurodegenerative diseases, such as Alzheimer’s disease. In this …
in the development of neurodegenerative diseases, such as Alzheimer’s disease. In this …
p38 MAPK signalling cascades in inflammatory disease
E Herlaar, Z Brown - Molecular medicine today, 1999 - cell.com
… Neutrophils stimulated with IL-8 can activate both the ERK pathway, which is PI3K-dependent,
and the p38 MAPK pathway, which is PI3K-independent 24 . However, the majority of …
and the p38 MAPK pathway, which is PI3K-independent 24 . However, the majority of …
The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer
HY Yong, MS Koh, A Moon - Expert opinion on investigational …, 2009 - Taylor & Francis
… Here, we review the isoforms of p38 MAPK, activation and function of p38 MAPK signaling
… This review summarizes p38 MAPK inhibitors used for inflammatory diseases and cancer. …
… This review summarizes p38 MAPK inhibitors used for inflammatory diseases and cancer. …
p38 MAPK signaling in oral-related diseases
CS Patil, KL Kirkwood - Journal of dental research, 2007 - journals.sagepub.com
… p38 MAPK signaling in chronic pain, temporomandibular joint disorders (TMJD), desquamative
disorders, … Finally, we will discuss p38 MAPK signaling and potential therapeutic targets. […
disorders, … Finally, we will discuss p38 MAPK signaling and potential therapeutic targets. […
The regulatory roles of mitogen-activated protein kinase (MAPK) pathways in health and diabetes: lessons learned from the pancreatic β-cell
V Sidarala, A Kowluru - Recent patents on endocrine …, 2016 - ingentaconnect.com
… to target MAPKs in the treatment of various diseases is pro… Antioxidants inhibit JNK and p38
MAPK activation but not ERK 1/2 … transduction pathway for the treatment of various diseases. …
MAPK activation but not ERK 1/2 … transduction pathway for the treatment of various diseases. …
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