Genetic risk, adherence to a healthy lifestyle, and coronary disease

AV Khera, CA Emdin, I Drake… - … England Journal of …, 2016 - Mass Medical Soc
… Although the absolute risk reduction that was … to a healthy lifestyle was greatest in the group
at high genetic risk, our results support public health efforts that emphasize a healthy lifestyle

Healthy lifestyle factors associated with lower risk of colorectal cancer irrespective of genetic risk

PR Carr, K Weigl, L Jansen, V Walter, V Erben… - Gastroenterology, 2018 - Elsevier
… and body fatness) and CRC risk. We created a genetic risk score, based on 53 risk variants,
… investigate the association of the healthy lifestyle score and risk of CRC, stratified by genetic

Genetic risk, adherence to a healthy lifestyle, and ischemic heart disease

TF Whayne, SP Saha - Current cardiology reports, 2019 - Springer
… future of genetic risk is an understanding of specific genes, a genetic risk score, specific genetic
loci … Healthy lifestyle is fashionably referred to as TLC and encompasses physical fitness, …

Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants

…, M Traylor, International Stroke Genetics Consortium - bmj, 2018 - bmj.com
lifestyle and genetic risk score. To obtain cumulative incidence for lifestyle and genetic risk
stratums we used competing risk … ratios for the genetic and lifestyle score in the risk of stroke …

[HTML][HTML] A healthy lifestyle in men at increased genetic risk for prostate cancer

A Plym, Y Zhang, KH Stopsack, B Delcoigne, F Wiklund… - European urology, 2023 - Elsevier
… This study examined whether the genetic risk of prostate cancer can be attenuated by a
healthy lifestyle including a healthy weight, regular exercise, not smoking, and a healthy diet. We …

Genetic risk for overall cancer and the benefit of adherence to a healthy lifestyle

M Zhu, T Wang, Y Huang, X Zhao, Y Ding, M Zhu, M Ji… - Cancer research, 2021 - AACR
… women having a favorable lifestyle. In summary, individuals at high genetic risk of overall
cancer can be identified by CPRS, and risk can be attenuated by adopting a healthy lifestyle. …

Genetic risk, a healthy lifestyle, and type 2 diabetes: the Dongfeng-Tongji cohort study

X Han, Y Wei, H Hu, J Wang, Z Li… - The Journal of …, 2020 - academic.oup.com
… a single lifestyle risk factor and genetic variants on diabetes risk (19… that a healthy lifestyle
might powerfully modify diabetes risk … ’s genetic risk profile, suggesting that benefits of lifestyle

Association of lifestyle and genetic risk with incidence of dementia

I Lourida, E Hannon, TJ Littlejohns, KM Langa… - Jama, 2019 - jamanetwork.com
… significant interaction between genetic risk and healthy lifestyle. Meaning A healthy lifestyle
was associated with lower risk of dementia among participants with low or high genetic risk. …

Association between genetic risk, adherence to healthy lifestyle behavior, and thyroid cancer risk

X Feng, F Wang, W Yang, Y Zheng, C Liu… - JAMA network …, 2022 - jamanetwork.com
… To examine the associations between genetics and healthy lifestyle with incident TC and
whether adherence to a healthy lifestyle modifies the association between genetic variants and …

[HTML][HTML] Estimation of absolute risk of colorectal cancer based on healthy lifestyle, genetic risk, and colonoscopy status in a population-based study

PR Carr, K Weigl, D Edelmann, L Jansen… - Gastroenterology, 2020 - Elsevier
risk of CRC in men and women. We observed a higher CRC risk in participants with high or
intermediate genetic riskrisk of CRC varied according to the polygenic risk score and the …