Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects

P Fontana, JS Hulot, P De Moerloose… - Journal of thrombosis …, 2007 - jthjournal.org
… Nevertheless, and for the first time, we show that a genetic variant (CYP2C19*2) is
associated with clopidogrel responsiveness in healthy subjects in two independent studies. …

Genetic polymorphisms and personality in healthy adults: a systematic review and meta-analysis

MR Munafo, TG Clark, LR Moore, E Payne… - Molecular …, 2003 - nature.com
… Association studies of genetic polymorphisms and personality in healthy adults (aged 16
or over) were included. Studies reporting data on male and female participants of any ethnic …

Influence of vitamin D receptor gene polymorphisms and 25-hydroxyvitamin D on blood pressure in apparently healthy subjects

S Muray, E Parisi, A Cardús, L Craver… - Journal of …, 2003 - journals.lww.com
… In summary, BsmI polymorphism of the VDR gene has shown an influence on BP in healthy
men. In the BB genotype BP levels were clearly lower and, only in them, vitamin D was …

Genetic polymorphisms and the impact of a higher clopidogrel dose regimen on active metabolite exposure and antiplatelet response in healthy subjects

T Simon, DL Bhatt, L Bergougnan… - Clinical …, 2011 - Wiley Online Library
… between genetic polymorphisms and clopidogrel in healthy … Finally, it is not clear that results
of healthy subjects can be … that, of the assessed polymorphic genes involved in clopi-H4 …

UGT2B17 Genetic Polymorphisms Dramatically Affect the Pharmacokinetics of MK‐7246 in Healthy Subjects in a First‐in‐Human Study

YH Wang, M Trucksis, JJ McElwee… - ClInICAl …, 2012 - Wiley Online Library
… In a first-in-human study, we investigated whether genetic polymorphisms contributed to
the … of UGT2B17 genetic polymorphisms and extensive first-pass metabolism of MK-7246. …

XRCC1 , XRCC3 , XPD gene polymorphisms, smoking and 32 P-DNA adducts in a sample of healthy subjects

G Matullo, D Palli, M Peluso, S Guarrera… - …, 2001 - academic.oup.com
… These polymorphisms, although generally associated with a … In the present study of 308
healthy adults from the Italian … levels, with genetic polymorphisms in three DNA repair genes, …

Frequencies of five genetic polymorphisms in coronarographed patients and effects on lipid levels in a supposedly healthy population

A Régis‐Bailly, S Visvikis, J Steinmetz… - … genetics, 1996 - Wiley Online Library
… Allele frequencies of genetic polymorphisms were compared between supposedly
healthy subjects and angiographically proven coronary artery disease patients. The …

Influence of CYP3A and CYP2C19 Genetic Polymorphisms on the Pharmacokinetics of Cilostazol in Healthy Subjects

HD Yoo, SA Park, HY Cho… - Clinical Pharmacology & …, 2009 - Wiley Online Library
… of genetic polymorphisms in the CYP3A and CYP2C19 genes on … a 50-mg single dose in
healthy subjects. CYP2C19 genotypes in … This indicates that CYP2C19 polymorphisms play an …

BDNF gene polymorphisms and haplotypes in relation to cognitive performance in Polish healthy subjects

M Wiłkość, A Szałkowska, M Skibińska… - Acta Neurobiologiae …, 2016 - ane.pl
genes should be carried out. Therefore, the main goal of the present study was to verify the
relationship between twelve BDNF gene polymorphisms … in 460 healthy subjects of Polish …

The effects of endothelial nitric oxide synthase gene polymorphisms on endothelial function and metabolic risk factors in healthy subjects: the significance of plasma …

A Imamura, R Takahashi, R Murakami… - European journal of …, 2008 - academic.oup.com
gene polymorphisms of eNOS have been detected; the eNOS G894T (Glu298Asp) and T–786C
polymorphisms, in … These eNOS gene polymorphisms have also been associated with …